Reddy Shweta Mary, Suresh Vasugi, Pitchiah Sivaperumal, Subramanian Balachandran
Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Cureus. 2023 Dec 10;15(12):e50284. doi: 10.7759/cureus.50284. eCollection 2023 Dec.
The extracts derived from red seaweed have shown characteristics that may reduce inflammation. The abovementioned effects can potentially provide positive outcomes in managing inflammatory illnesses, including arthritis, inflammatory bowel disease, and other skin problems.
The polysaccharides were isolated from the species. The water-soluble polysaccharides were extracted and fractionated from several Indian seaweeds (Red) using a simple, cost-effective approach. Anti-inflammatory effects were further evaluated and validated by FTIR and FESEM analyses.
FT-IR and FESEM were used to assess the structural features of polysaccharides and the surface morphology. In addition, the red seaweed species of the genus , which includes polysaccharides, was shown to significantly inhibit the denaturation of bovine serum albumin (BSA), further proving that the substance has anti-inflammatory qualities.
In this work, an assay to suppress protein activity was utilized to investigate the potential anti-inflammatory effects of polysaccharides derived from As predicted, increasing concentrations of the extract, ranging from 25 to 100 µg/ml, led to a rise in the percentage of inhibited protein denaturation.
A statistically significant difference was found between these findings and those obtained with aspirin, a commonly used non-steroidal anti-inflammatory medicine (NSAID). The red algae that grow in the shallow waters of the southern Indian Ocean may be used in medicine.
红海藻提取物已显示出可能减轻炎症的特性。上述作用在治疗包括关节炎、炎症性肠病和其他皮肤问题在内的炎症性疾病方面可能产生积极效果。
从该物种中分离多糖。采用一种简单、经济高效的方法从几种印度红海藻中提取并分离出水溶性多糖。通过傅里叶变换红外光谱（FTIR）和场发射扫描电子显微镜（FESEM）分析进一步评估和验证其抗炎作用。
利用傅里叶变换红外光谱（FT - IR）和场发射扫描电子显微镜（FESEM）评估多糖的结构特征和表面形态。此外，包括多糖的该属红海藻物种被证明能显著抑制牛血清白蛋白（BSA）的变性，进一步证明该物质具有抗炎特性。
在这项工作中，利用一种抑制蛋白质活性的测定方法来研究源自……的多糖的潜在抗炎作用。正如预期的那样，提取物浓度从25微克/毫升增加到100微克/毫升，导致蛋白质变性抑制百分比上升。
这些结果与常用的非甾体抗炎药阿司匹林的结果之间存在统计学上的显著差异。生长在印度洋南部浅水区的红藻可能可用于医学。
