Unidad de Diseño y Desarrollo, Fundación Oftalmológica de Santander, Floridablanca, Colombia.
Unidad de Diseño y Desarrollo, Fundación Oftalmológica de Santander, Floridablanca, Colombia; Facultad de Ciencias de la Salud, Universidad Autónoma de Bucaramanga, Bucaramanga,.
Biomedica. 2023 Dec 29;43(Sp. 3):51-65. doi: 10.7705/biomedica.7077.
Introduction. Non-communicable chronic diseases represent the leading cause of death worldwide, and their prevalence is increasing due to the epidemiological transition. Despite the advances in their management, control rates are deficient, attributed to multiple factors like adherence to pharmacological treatment, one of the most significant and least studied in the Colombian population. Objective. To calculate adherence to treatment in Colombian patients with arterial hypertension, cerebrovascular disease, diabetes mellitus, asthma, chronic obstructive pulmonary disease, and dyslipidemia between 2005 and 2022. Materials and methods. We performed a systematic literature review and a meta-analysis of studies identified through the Medline and LILACS databases to quantitatively synthesize treatment adherence percentage. Results. Fourteen studies met the inclusion criteria, and 5,658 patients were analyzed. The treatment adherence was 59%, with significant heterogeneity among the included studies (95% CI= 46- 71%; I2 = 98.8%, p< 0.001). Higher adherence rates were observed for diabetes mellitus (79%; 95% CI = 65- 90%) and dyslipidemia (70%; 95% CI = 66- 74%). Adherence to arterial hypertension treatment was 51% (95 %; CI = 31- 72%). Conclusions. This systematic review showed low adherence to recommendations regarding pharmacological management in non-communicable chronic diseases, which can have implications for long-term clinical outcomes and disease burden.
简介。非传染性慢性疾病是全球主要的死亡原因，由于流行病学的转变，其患病率正在上升。尽管在管理方面取得了进展，但控制率仍存在不足，这归因于多种因素，如对药物治疗的依从性，这是在哥伦比亚人群中研究最少但最重要的因素之一。目的。计算 2005 年至 2022 年间哥伦比亚患有动脉高血压、脑血管疾病、糖尿病、哮喘、慢性阻塞性肺疾病和血脂异常的患者对治疗的依从性。材料和方法。我们通过 Medline 和 LILACS 数据库进行了系统的文献综述和荟萃分析，以定量综合治疗依从性百分比。结果。符合纳入标准的研究有 14 项，共分析了 5658 名患者。治疗依从性为 59%，纳入的研究之间存在显著异质性（95%CI=46-71%；I2=98.8%，p<0.001）。糖尿病（79%；95%CI=65-90%）和血脂异常（70%；95%CI=66-74%）的依从率较高。动脉高血压治疗的依从率为 51%（95%CI=31-72%）。结论。本系统综述表明，非传染性慢性疾病药物治疗的建议依从性较低，这可能对长期临床结果和疾病负担产生影响。
