Tarazona Sonia, Arzalluz-Luque Angeles, Conesa Ana
Department of Applied Statistics, Operations Research and Quality, Universitat Politècnica de València, Valencia, Spain.
Microbiology and Cell Science Department, Institute for Food and Agricultural Research, University of Florida, Gainesville, FL, USA.
Nat Comput Sci. 2021 Jun;1(6):395-402. doi: 10.1038/s43588-021-00086-z. Epub 2021 Jun 21.
Multi-omics approaches have become a reality in both large genomics projects and small laboratories. However, the multi-omics research community still faces a number of issues that have either not been sufficiently discussed or for which current solutions are still limited. In this Perspective, we elaborate on these limitations and suggest points of attention for future research. We finally discuss new opportunities and challenges brought to the field by the rapid development of single-cell high-throughput molecular technologies.
多组学方法在大型基因组学项目和小型实验室中都已成为现实。然而，多组学研究群体仍然面临一些尚未得到充分讨论的问题，或者目前的解决方案仍然有限的问题。在这篇观点文章中，我们详细阐述了这些局限性，并提出了未来研究的注意要点。我们最后讨论了单细胞高通量分子技术的快速发展给该领域带来的新机遇和挑战。
