Petrov N A, Netesov S V, Blinov V M, Vasilenko S K
Mol Gen Mikrobiol Virusol. 1986 Nov(11):7-14.
An evolutional tree of human influenza viruses of the H3N2-subtype is suggested on the basis of combined published primary structures of the hemagglutinin HA1-subunit. Possible differences between natural and sequenced structures are discussed. A tendency to reversions in the course of antigenic draft within the subtype has been revealed to support the hypothesis of limited antigenic evolution within a single subtype.
基于已发表的血凝素HA1亚基一级结构的综合信息,构建了H3N2亚型人流感病毒的进化树。讨论了天然结构与测序结构之间可能存在的差异。已揭示出该亚型抗原漂移过程中的回复突变倾向,这支持了单一亚型内抗原进化有限的假说。