Scholl T O, Miller L K, Salmon R W, Cofsky M C, Shearer J
Obstet Gynecol. 1987 Mar;69(3 Pt 1):312-6.
A prospective study of 757 adolescents who gave birth to singleton live-born infants was undertaken to assess effects of prenatal care on pregnancy outcome. The analysis indicated that the odds of low pregnancy weight gain for gestation was reduced by a factor of two (odds ratio = 0.50, P less than .05) for adolescents with adequate prenatal care; the risk of preterm delivery was reduced with both adequate (odds ratio = 0.34, P less than .01) and intermediate prenatal care (odds ratio = 0.46, P less than .05). Birth weight was increased by an average of 157 g with adequate care (P less than .05) and 107 g with intermediate care (P less than .05). After adjusting for pregnancy weight gain and preterm delivery, differences in birth weight were much smaller and no longer statistically significant, suggesting indirect effects of care on birth weight (ie, improvements in weight gain adequacy and in preterm delivery).
对757名分娩单胎活产婴儿的青少年进行了一项前瞻性研究，以评估产前护理对妊娠结局的影响。分析表明，接受充分产前护理的青少年，孕期体重增加不足的几率降低了一半（比值比=0.50，P<0.05）；充分产前护理（比值比=0.34，P<0.01）和中等产前护理（比值比=0.46，P<0.05）均可降低早产风险。充分护理使出生体重平均增加157克（P<0.05），中等护理使出生体重平均增加107克（P<0.05）。在对孕期体重增加和早产进行调整后，出生体重的差异要小得多，且不再具有统计学意义，这表明护理对出生体重有间接影响（即体重增加充足率和早产情况得到改善）。
