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一例罕见的颈椎椎间盘炎病例。

A Rare Case of Cervical Spondylodiscitis.

作者信息

Hong Angelina, Alvi Ali Tariq, Lim Lily Hyunjung, Aneja Pallavi

机构信息

HCA Florida Westside Hospital, Plantation, FL.

出版信息

HCA Healthc J Med. 2023 Dec 30;4(6):425-428. doi: 10.36518/2689-0216.1577. eCollection 2023.

Abstract

INTRODUCTION

Invasive candidiasis can lead to numerous life-threatening sequelae. is the second-most common causative species of invasive candidiasis. This species possesses a high risk for persistent infection and candidemia. An uncommon complication of invasive candidiasis is spondylodiscitis and can rarely affect the cervical spine.

CASE PRESENTATION

The patient is a female in her late 50s with a complex medical history inclusive of chronic obstructive pulmonary disease, chronic pain, multiple abdominal surgeries, prolonged intensive care unit admission, and administration of total parenteral nutrition and broad-spectrum antibiotics who presented with complaints of worsening neck pain. She was last hospitalized 3 months prior and found to have fungemia but was nonadherent to antifungal therapy.She was found to have advanced C5-6 spondylodiscitis and an epidural abscess. Her surgical cultures grew . Despite surgical intervention and antimicrobial therapy, she clinically deteriorated and acquired septic shock with multiorgan failure.

CONCLUSION

This is a rare case of cervical spondylodiscitis caused by a deep-seated infection.

摘要

引言

侵袭性念珠菌病可导致众多危及生命的后遗症。 是侵袭性念珠菌病的第二大常见致病菌种。该菌种存在持续感染和念珠菌血症的高风险。侵袭性念珠菌病的一种罕见并发症是脊椎间盘炎,很少累及颈椎。

病例介绍

患者为一名50多岁的女性,有复杂的病史,包括慢性阻塞性肺疾病、慢性疼痛、多次腹部手术、长时间入住重症监护病房以及接受全胃肠外营养和广谱抗生素治疗,她因颈部疼痛加重前来就诊。她3个月前最后一次住院,被发现患有 真菌血症,但未坚持抗真菌治疗。她被发现患有晚期C5 - 6脊椎间盘炎和硬膜外脓肿。她的手术培养物培养出 。尽管进行了手术干预和抗菌治疗,但她的病情在临床上仍恶化,并出现了感染性休克和多器官功能衰竭。

结论

这是一例由深部 感染引起的颈椎脊椎间盘炎罕见病例。

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本文引用的文献

1
A Rare Case of Candida parapsilosis Lumbar Discitis With Osteomyelitis.
Cureus. 2022 Jun 15;14(6):e25955. doi: 10.7759/cureus.25955. eCollection 2022 Jun.
2
Candidemia and Invasive Candidiasis.
Infect Dis Clin North Am. 2021 Jun;35(2):389-413. doi: 10.1016/j.idc.2021.03.007.
3
A Review on Molecular Mechanisms of Antifungal Resistance in : Update and Recent Advances.
Microb Drug Resist. 2021 Oct;27(10):1371-1388. doi: 10.1089/mdr.2020.0235. Epub 2021 May 5.
4
Invasive candidiasis.
Nat Rev Dis Primers. 2018 May 11;4:18026. doi: 10.1038/nrdp.2018.26.
5
A rare case of Candida glabrata spondylodiscitis: case report and literature review.
Int J Infect Dis. 2018 Mar;68:31-35. doi: 10.1016/j.ijid.2018.01.003. Epub 2018 Jan 12.
6
Cervical Spondylodiscitis: Presentation, Timing, and Surgical Management in 59 Patients.
World Neurosurg. 2017 Jul;103:664-670. doi: 10.1016/j.wneu.2017.04.119. Epub 2017 Apr 27.
8
Candidemia and invasive candidiasis in adults: A narrative review.
Eur J Intern Med. 2016 Oct;34:21-28. doi: 10.1016/j.ejim.2016.06.029. Epub 2016 Jul 7.
9
Invasive Candidiasis.
N Engl J Med. 2015 Oct 8;373(15):1445-56. doi: 10.1056/NEJMra1315399.
10
Echinocandin resistance: an emerging clinical problem?
Curr Opin Infect Dis. 2014 Dec;27(6):484-92. doi: 10.1097/QCO.0000000000000111.

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