Hong Angelina, Alvi Ali Tariq, Lim Lily Hyunjung, Aneja Pallavi
HCA Florida Westside Hospital, Plantation, FL.
HCA Healthc J Med. 2023 Dec 30;4(6):425-428. doi: 10.36518/2689-0216.1577. eCollection 2023.
Invasive candidiasis can lead to numerous life-threatening sequelae. is the second-most common causative species of invasive candidiasis. This species possesses a high risk for persistent infection and candidemia. An uncommon complication of invasive candidiasis is spondylodiscitis and can rarely affect the cervical spine.
The patient is a female in her late 50s with a complex medical history inclusive of chronic obstructive pulmonary disease, chronic pain, multiple abdominal surgeries, prolonged intensive care unit admission, and administration of total parenteral nutrition and broad-spectrum antibiotics who presented with complaints of worsening neck pain. She was last hospitalized 3 months prior and found to have fungemia but was nonadherent to antifungal therapy.She was found to have advanced C5-6 spondylodiscitis and an epidural abscess. Her surgical cultures grew . Despite surgical intervention and antimicrobial therapy, she clinically deteriorated and acquired septic shock with multiorgan failure.
This is a rare case of cervical spondylodiscitis caused by a deep-seated infection.
侵袭性念珠菌病可导致众多危及生命的后遗症。 是侵袭性念珠菌病的第二大常见致病菌种。该菌种存在持续感染和念珠菌血症的高风险。侵袭性念珠菌病的一种罕见并发症是脊椎间盘炎，很少累及颈椎。
患者为一名50多岁的女性，有复杂的病史，包括慢性阻塞性肺疾病、慢性疼痛、多次腹部手术、长时间入住重症监护病房以及接受全胃肠外营养和广谱抗生素治疗，她因颈部疼痛加重前来就诊。她3个月前最后一次住院，被发现患有 真菌血症，但未坚持抗真菌治疗。她被发现患有晚期C5 - 6脊椎间盘炎和硬膜外脓肿。她的手术培养物培养出 。尽管进行了手术干预和抗菌治疗，但她的病情在临床上仍恶化，并出现了感染性休克和多器官功能衰竭。
这是一例由深部 感染引起的颈椎脊椎间盘炎罕见病例。
