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使用蒙特卡罗GATE模拟对放射治疗应用中基于-的体模材料进行剂量分析。

Dosimetric Analysis of -based Phantom Material in Radiation Therapy Applications Using Monte Carlo GATE Simulation.

作者信息

Zuber Siti Hajar, Hadi Muhammad Fahmi Rizal Abdul, Samson Damilola Oluwafemi, Jayamani Jayapramila, Rabaiee Nor Ain, Aziz Mohd Zahri Abdul, Hashikin Nurul Ab Aziz, Ying Chee Keat, Yusof Mohd Fahmi Mohd, Hashim Rokiah

机构信息

Diagnostic Imaging and Radiotherapy, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Malaysia.

School of Physics, Universiti Sains Malaysia, 11800, Penang, Malaysia.

出版信息

J Med Phys. 2023 Oct-Dec;48(4):358-364. doi: 10.4103/jmp.jmp_75_23. Epub 2023 Dec 5.

Abstract

PURPOSE

This study aims to determine the percentage depth dose (PDD) of a phantom material made from soy-lignin bonded spp. particleboard coated with a gloss finish by using Monte Carlo Geant4 Application for Tomographic Emission (GATE) simulation.

MATERIALS AND METHODS

The particleboard was fabricated using a hot pressing technique at target density of 1.0 g·cm and the elemental fraction was recorded for the simulation. The PDD was simulated in the GATE simulation using the linear accelerator Elekta Synergy model for the water phantom and phantom, and the results were compared with the experimental PDD performed by several studies. Beam flatness and beam symmetry were also measured in this study.

RESULTS

The simulated PDD for and water was in agreement with the experimental PDD of water with overall discrepancies of 0% to 8.7% at depth ranging from 1.0 to 15.0 cm. In the GATE simulation, all the points passed the clinical 3%/3 mm criterion in comparison with water, with the final percentage of 2.34% for phantom and 2.49% for the water phantom simulated in GATE. Both the symmetries are all within the range of an acceptable value of 2.0% according to the recommendation, with the beam symmetry of the water phantom and phantom at 0.58% and 0.28%, respectively.

CONCLUSIONS

The findings of this study provide the necessary foundation to confidently use the phantom for radiotherapy purposes, especially in treatment planning.

摘要

目的

本研究旨在通过使用蒙特卡洛Geant4断层发射应用程序(GATE)模拟,确定由涂有光泽漆的大豆木质素粘结的spp.刨花板制成的体模材料的百分深度剂量(PDD)。

材料与方法

采用热压技术在目标密度为1.0 g·cm的条件下制造刨花板,并记录元素分数用于模拟。在GATE模拟中,使用直线加速器Elekta Synergy模型对水体模和体模的PDD进行模拟,并将结果与多项研究进行的实验PDD进行比较。本研究还测量了射野平坦度和射野对称性。

结果

体模和水的模拟PDD与水的实验PDD一致,在1.0至15.0 cm深度范围内,总体差异为0%至8.7%。在GATE模拟中,与水相比,所有点均通过了临床3%/3 mm标准,GATE模拟中体模的最终百分比为2.34%,水体模为2.49%。根据建议,两种对称性均在可接受值2.0%的范围内,水体模和体模的射野对称性分别为0.58%和0.28%。

结论

本研究结果为自信地将该体模用于放射治疗目的,尤其是治疗计划,提供了必要的基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd69/10783191/71b0647a7313/JMP-48-358-g001.jpg

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