Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA.
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
EuroIntervention. 2024 Jan 15;20(2):e123-e134. doi: 10.4244/EIJ-D-23-00448.
Increasing evidence has shown that coronary spasm and vasomotor dysfunction may be the underlying cause in more than half of myocardial infarctions with non-obstructive coronary arteries (MINOCA) as well as an important cause of chronic chest pain in the outpatient setting. We review the contemporary understanding of coronary spasm and related vasomotor dysfunction of the coronary arteries, the pathophysiology and prognosis, and current and emerging approaches to diagnosis and evidence-based treatment.
越来越多的证据表明，冠状动脉痉挛和血管舒缩功能障碍可能是半数以上非阻塞性冠状动脉心肌梗死（MINOCA）的根本原因，也是门诊慢性胸痛的重要原因。我们回顾了对冠状动脉痉挛和相关冠状动脉血管舒缩功能障碍的现代认识，包括病理生理学和预后，以及目前和新兴的诊断方法和循证治疗。
