一项通过即时适应的活动和饮食干预来降低血压的研究：myBPmyLife 研究的基本原理和设计。

A Physical Activity and Diet Just-in-Time Adaptive Intervention to Reduce Blood Pressure: The myBPmyLife Study Rationale and Design.

机构信息

Division of Cardiovascular Medicine, Department of Internal Medicine University of Michigan Ann Arbor MI USA.

Michigan Integrated Center for Health Analytics and Medical Prediction University of Michigan Ann Arbor MI USA.

出版信息

J Am Heart Assoc. 2024 Jan 16;13(2):e031234. doi: 10.1161/JAHA.123.031234.

DOI:10.1161/JAHA.123.031234

PMID:38226507

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10926831/

Abstract

BACKGROUND

Smartphone applications and wearable devices are promising mobile health interventions for hypertension self-management. However, most mobile health interventions fail to use contextual data, potentially diminishing their impact. The myBPmyLife Study is a just-in-time adaptive intervention designed to promote personalized self-management for patients with hypertension.

METHODS AND RESULTS

The study is a 6-month prospective, randomized-controlled, remotely administered trial. Participants were recruited from the University of Michigan Health in Ann Arbor, Michigan or the Hamilton Community Health Network, a federally qualified health center network in Flint, Michigan. Participants were randomized to a mobile application with a just-in-time adaptive intervention promoting physical activity and lower-sodium food choices as well as weekly goal setting or usual care. The mobile study application encourages goal attainment through a central visualization displaying participants' progress toward their goals for physical activity and lower-sodium food choices. Participants in both groups are followed for up for 6 months with a primary end point of change in systolic blood pressure. Exploratory analyses will examine the impact of notifications on step count and self-reported lower-sodium food choices. The study launched on December 9, 2021, with 484 participants enrolled as of March 31, 2023. Enrollment of participants was completed on July 3, 2023. After 6 months of follow-up, it is expected that results will be available in the spring of 2024.

CONCLUSIONS

The myBPmyLife study is an innovative mobile health trial designed to evaluate the effects of a just-in-time adaptive intervention focused on improving physical activity and dietary sodium intake on blood pressure in diverse patients with hypertension.

REGISTRATION

URL: https://www.clinicaltrials.gov; Unique identifier: NCT05154929.

摘要

背景

智能手机应用程序和可穿戴设备是有前途的移动健康干预措施，可用于高血压的自我管理。然而，大多数移动健康干预措施未能利用情境数据，从而可能降低其效果。myBPmyLife 研究是一项即时自适应干预研究，旨在为高血压患者促进个性化自我管理。

方法和结果

该研究是一项为期 6 个月的前瞻性、随机对照、远程管理试验。参与者从密歇根大学健康系统安娜堡分校或位于密歇根州弗林特的 Hamilton 社区健康网络（一个有联邦资质的健康中心网络）招募。参与者被随机分配到一个具有即时自适应干预功能的移动应用程序，该应用程序旨在促进身体活动和低钠食物选择以及每周设定目标，或常规护理。移动研究应用程序通过中央可视化显示参与者在身体活动和低钠食物选择目标方面的进展，鼓励目标的实现。两组参与者都将随访 6 个月，主要终点为收缩压的变化。探索性分析将检查通知对步数和自我报告的低钠食物选择的影响。该研究于 2021 年 12 月 9 日启动，截至 2023 年 3 月 31 日，已有 484 名参与者入组。2023 年 7 月 3 日完成了参与者的入组。在 6 个月的随访后，预计结果将于 2024 年春季公布。