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Mechanisms of SOSS-Integrator-PP2A complex in attenuating R-loops and promoting genome stability.

作者信息

Wang Jingwen, Xu Conglin, Zhang Zhen, Chen Fei Xavier

机构信息

Department of Radiation Oncology, Shanghai Medical College, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.

Department of Oncology, Shanghai Medical College, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.

出版信息

Clin Transl Med. 2024 Jan;14(1):e1519. doi: 10.1002/ctm2.1519.

DOI:10.1002/ctm2.1519

PMID:38226796

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10790593/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/837c/10790593/a46b94cc40fd/CTM2-14-e1519-g001.jpg

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Nature. 2023 Sep;621(7979):610-619. doi: 10.1038/s41586-023-06515-5. Epub 2023 Aug 9.

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Nat Rev Mol Cell Biol. 2020 Mar;21(3):167-178. doi: 10.1038/s41580-019-0206-3. Epub 2020 Jan 31.

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DNA Cell Biol. 2020 Nov;39(11):1914-1925. doi: 10.1089/dna.2020.5906. Epub 2020 Oct 14.

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R-loop-dependent promoter-proximal termination ensures genome stability.

Nature. 2023 Sep;621(7979):610-619. doi: 10.1038/s41586-023-06515-5. Epub 2023 Aug 9.

R-loop-derived cytoplasmic RNA-DNA hybrids activate an immune response.

Nature. 2023 Jan;613(7942):187-194. doi: 10.1038/s41586-022-05545-9. Epub 2022 Dec 21.

Targeting DNA damage response pathways in cancer.

Nat Rev Cancer. 2023 Feb;23(2):78-94. doi: 10.1038/s41568-022-00535-5. Epub 2022 Dec 5.

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Nat Rev Mol Cell Biol. 2022 Aug;23(8):521-540. doi: 10.1038/s41580-022-00474-x. Epub 2022 Apr 22.

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Mechanisms of SOSS-Integrator-PP2A complex in attenuating R-loops and promoting genome stability.

作者信息

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出版信息

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