Kasdan M L, Janes C
Plast Reconstr Surg. 1987 Mar;79(3):456-62. doi: 10.1097/00006534-198703000-00027.
We reviewed 1075 patients presenting over a 12-year period with symptoms of carpal tunnel syndrome. A total of 994 had a final diagnosis of carpal tunnel syndrome. There were 444 male and 550 female patients with a mean age of 42 years. Three-hundred and ninety-five related symptoms to their job. Surgery was performed in 27 percent of the total diagnosed cases with approximately 97 percent relief of symptoms. Satisfactory alleviation of symptoms was obtained in 14.3 percent of patients treated conservatively prior to 1980, with one or a combination of splinting anti-inflammatory agents, job or activity change, and steroid injections. In 1980, vitamin B6 (pyridoxine) was added as a method of conservative treatment. Satisfactory improvement was obtained in 68 percent of 494 patients treated with a controlled dosage (100 mg b.i.d.). While our findings were not the result of a controlled scientific study, we feel they suggest that regulated use of vitamin B6 may be helpful in treating many cases of carpal tunnel syndrome.
我们回顾了1075例在12年期间出现腕管综合征症状的患者。共有994例最终被诊断为腕管综合征。其中男性444例，女性550例，平均年龄42岁。395例症状与工作有关。在所有确诊病例中，27%的患者接受了手术治疗，术后症状缓解率约为97%。1980年以前，14.3%接受保守治疗的患者通过使用夹板、抗炎药、改变工作或活动以及注射类固醇中的一种或几种联合治疗，症状得到了满意缓解。1980年，添加了维生素B6（吡哆醇）作为一种保守治疗方法。494例接受控制剂量（每日两次，每次100毫克）治疗的患者中，68%症状得到满意改善。虽然我们的研究结果并非来自对照科学研究，但我们认为这些结果表明，规范使用维生素B6可能有助于治疗许多腕管综合征病例。
