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维生素B6治疗腕管综合征:一项双盲研究。

Treatment of carpal tunnel syndrome with vitamin B6: a double-blind study.

作者信息

Stransky M, Rubin A, Lava N S, Lazaro R P

机构信息

Department of Neurology, Albany Medical College, NY 12208.

出版信息

South Med J. 1989 Jul;82(7):841-2. doi: 10.1097/00007611-198907000-00011.

DOI:10.1097/00007611-198907000-00011
PMID:2749352
Abstract

We undertook a randomized, double-blind, placebo-controlled study to investigate the therapeutic effect of vitamin B6 on carpal tunnel syndrome. After ten weeks in the study, ten of 15 patients improved (this included patients given placebo and those given no treatment). Vitamin B6 seems to have no advantage over conservative therapy for carpal tunnel syndrome. This study also suggests that repeat electrodiagnostic testing is no more useful than clinical symptoms in deciding on surgical intervention after unsuccessful conservative therapy.

摘要

我们进行了一项随机、双盲、安慰剂对照研究,以调查维生素B6对腕管综合征的治疗效果。研究进行十周后,15名患者中有10名病情有所改善(这包括接受安慰剂治疗的患者和未接受治疗的患者)。对于腕管综合征,维生素B6似乎并不比保守治疗更具优势。这项研究还表明,在保守治疗失败后决定是否进行手术干预时,重复进行电诊断测试并不比临床症状更有用。

相似文献

1
Treatment of carpal tunnel syndrome with vitamin B6: a double-blind study.维生素B6治疗腕管综合征:一项双盲研究。
South Med J. 1989 Jul;82(7):841-2. doi: 10.1097/00007611-198907000-00011.
2
Pyridoxine hydrochloride treatment of carpal tunnel syndrome: a review.
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Treatment of carpal tunnel syndrome with vitamin B6.用维生素B6治疗腕管综合征。
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Brief communication: effect of pharmacologic doses of vitamin B6 on carpal tunnel syndrome, electroencephalographic results, and pain.简短通讯:药理剂量的维生素B6对腕管综合征、脑电图结果及疼痛的影响
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Carpal tunnel syndrome and vitamin B6.腕管综合征与维生素B6
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Carpal tunnel syndrome: current theory, treatment, and the use of B6.腕管综合征:当前理论、治疗方法及维生素B6的应用
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Electromyographic data differentiate patients with the carpal tunnel syndrome when double blindly treated with pyridoxine and placebo.当用吡哆醇和安慰剂进行双盲治疗时,肌电图数据可区分患有腕管综合征的患者。
Res Commun Chem Pathol Pharmacol. 1983 Sep;41(3):501-11.

引用本文的文献

1
Concurrent musculoskeletal and soft tissue pain in the upper extremity can affect the treatment and prognosis of carpal tunnel syndrome: redefining a common condition.上肢同时存在的肌肉骨骼和软组织疼痛会影响腕管综合征的治疗和预后:重新定义一种常见病症。
J Pain Res. 2017 Oct 24;10:2497-2502. doi: 10.2147/JPR.S142153. eCollection 2017.
2
Effect of vitamin b6 on clinical symptoms and electrodiagnostic results of patients with carpal tunnel syndrome.维生素B6对腕管综合征患者临床症状及电诊断结果的影响。
Adv Pharm Bull. 2013;3(2):283-8. doi: 10.5681/apb.2013.046. Epub 2013 Aug 20.
3
Carpal tunnel syndrome.
腕管综合征
BMJ Clin Evid. 2010 Mar 23;2010:1114.
4
Placebo interventions for all clinical conditions.针对所有临床病症的安慰剂干预措施。
Cochrane Database Syst Rev. 2010 Jan 20;2010(1):CD003974. doi: 10.1002/14651858.CD003974.pub3.
5
Randomized clinical trial of surgery versus conservative therapy for carpal tunnel syndrome [ISRCTN84286481].腕管综合征手术与保守治疗的随机临床试验[国际标准随机对照试验编号:ISRCTN84286481]
BMC Musculoskelet Disord. 2005 Jan 18;6:2. doi: 10.1186/1471-2474-6-2.
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What can family physicians offer patients with carpal tunnel syndrome other than surgery? A systematic review of nonsurgical management.除了手术之外,家庭医生能为腕管综合征患者提供什么?非手术治疗的系统评价。
Ann Fam Med. 2004 May-Jun;2(3):267-73. doi: 10.1370/afm.21.
7
Non-surgical treatment (other than steroid injection) for carpal tunnel syndrome.腕管综合征的非手术治疗(类固醇注射除外)
Cochrane Database Syst Rev. 2003;2003(1):CD003219. doi: 10.1002/14651858.CD003219.
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Response of carpal tunnel syndrome to hormone replacement therapy.腕管综合征对激素替代疗法的反应。
BMJ. 1991 Dec 14;303(6816):1514. doi: 10.1136/bmj.303.6816.1514.