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巨大肺内孤立性纤维瘤

Giant intrapulmonary solitary fibrous tumor.

作者信息

Shivalingaiah Sheela Devi Chandakavadi, Gurumurthy Deepika, Dadich Gauri

机构信息

Jagadguru Sri Shivarathreeshwara Academy of Higher Education & Research (JSSAHER), Department of Pathology, Mysore, Karnataka, India.

出版信息

Autops Case Rep. 2024 Jun 21;14:e2024494. doi: 10.4322/acr.2024.494. eCollection 2024.

DOI:10.4322/acr.2024.494
PMID:39021462
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11253912/
Abstract

Solitary fibrous tumor (SFT) is a soft tissue tumor of mesenchymal origin involving, most commonly, the pleura. Intrapulmonary SFT is a slow-growing tumor that rarely reaches giant forms. SFTs are asymptomatic and often randomly discovered by routine chest X-rays. The diagnosis requires histopathological and immunohistochemical (IHC) examinations. Most of the SFTs are benign and present an indolent course. Larger tumors are more likely to be malignant and consequently associated with a worse prognosis. Despite having histopathological criteria for malignancy, the behavior of SFTs is challenging to predict. We report a case of giant intrapulmonary SFT of intermediate risk.

摘要

孤立性纤维瘤(SFT)是一种间叶组织来源的软组织肿瘤,最常见于胸膜。肺内SFT是一种生长缓慢的肿瘤,很少发展为巨大型。SFT通常无症状,常通过常规胸部X线检查偶然发现。诊断需要组织病理学和免疫组织化学(IHC)检查。大多数SFT是良性的,病程进展缓慢。较大的肿瘤更有可能是恶性的,因此预后较差。尽管有恶性肿瘤的组织病理学标准,但SFT的行为难以预测。我们报告一例具有中等风险的巨大型肺内SFT病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/590b/11253912/b4279503139b/autopsy-14-e2024494-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/590b/11253912/8b9543e44b8a/autopsy-14-e2024494-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/590b/11253912/b4279503139b/autopsy-14-e2024494-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/590b/11253912/8b9543e44b8a/autopsy-14-e2024494-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/590b/11253912/b4279503139b/autopsy-14-e2024494-g02.jpg

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孤立性纤维瘤的多面性;组织学特征的多样性、鉴别诊断以及分子研究和替代标志物在避免误诊和预测行为中的作用。
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