Department of Urology, Sakarya University, Training and Research Hospital, Sakarya, Turkey.
Faculty of Medicine, Department of Urology, Sakarya University, Sakarya, Turkey.
Int Urol Nephrol. 2024 Jun;56(6):1927-1933. doi: 10.1007/s11255-023-03909-2. Epub 2024 Jan 19.
There is a growing interest in reconstructive urology and female urethroplasty. We aimed to report our experience in ventral-onlay buccal mucosa graft (BMG) urethroplasty supported with Martius flap (MF) in treating female urethral stricture disease.
We retrospectively evaluated data of 18 female patients (ages 35-78) who were diagnosed with urethral stricture disease and underwent ventral-onlay BMG urethroplasty supported with MF by single surgeon in a tertiary referral centre between February 2019 and October 2022. Detailed history, international prostate symptom score (IPSS), pelvic examination, urine flow rate (rate and pattern), post void residual (PVR), storage and voiding phase urodynamic study, and voiding cystourethrography were recorded. At the last visit; the number of urethral dilatations before urethroplasty, time from urethral dilation to urethroplasty, hospital stay, urethral catheterization time, postoperative IPSS, PVR and uroflowmetry values were recorded.
The presenting symptoms were obstructive voiding symptoms in 16 patients. While the mean number of urethral dilatation was 2.11 ± 1.93 (1-7), the mean time from dilatation to urethroplasty was 5.83 ± 5.00 (1-19 months) months. Maximum flow rate increased from 8.36 ± 3.26 ml/sec in preoperative uroflowmetry to 21.45 ± 5.27 ml/sec at the last follow-up (p < 0.001). Post-void residual urine (PVR) decreased from preoperative mean 116.66 ± 105.88 cc to 26.94 ± 22.69 cc postoperatively (p < 0.004). None of the patients developed stricture recurrence, incontinence or vaginal fistula until the last follow-up. The mean follow-up period was 17.28 ± 11.65 (1-35) months.
A ventral-onlay BMG urethroplasty supported with MF represents an effective and reproducible treatment option for FUS in the present study.
重建泌尿科和女性尿道成形术越来越受到关注。我们旨在报告我们在使用 Martius 皮瓣(MF)支撑的腹侧黏膜下颊黏膜移植物(BMG)尿道成形术治疗女性尿道狭窄疾病方面的经验。
我们回顾性评估了 2019 年 2 月至 2022 年 10 月期间,一位主治医生在一家三级转诊中心对 18 名女性患者(年龄 35-78 岁)进行腹侧黏膜下颊黏膜移植物(BMG)尿道成形术并使用 MF 支撑治疗女性尿道狭窄疾病的数据。详细记录了病史、国际前列腺症状评分(IPSS)、骨盆检查、尿流率(速率和模式)、残余尿量(PVR)、储存和排空阶段尿动力学研究以及排尿膀胱尿道造影。在最后一次就诊时,记录了尿道成形术前尿道扩张的次数、尿道扩张到尿道成形术的时间、住院时间、尿道置管时间、术后 IPSS、PVR 和尿流率值。
16 例患者的首发症状为排尿梗阻症状。而尿道扩张的平均次数为 2.11±1.93(1-7 次),尿道扩张到尿道成形术的平均时间为 5.83±5.00(1-19 个月)。术前尿流率最大流量从 8.36±3.26ml/sec 增加到最后一次随访时的 21.45±5.27ml/sec(p<0.001)。术后残余尿量(PVR)从术前平均 116.66±105.88cc 减少到 26.94±22.69cc(p<0.004)。截至最后一次随访,所有患者均未出现狭窄复发、尿失禁或阴道瘘。平均随访时间为 17.28±11.65(1-35)个月。
在本研究中,使用 MF 支撑的腹侧黏膜下颊黏膜移植物尿道成形术是一种有效且可重复的治疗女性尿道狭窄的方法。