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肥胖和血脂相关指标是中国中老年人群高血压的危险因素:一项横断面研究。

Obesity-and lipid-related indices as a risk factor of hypertension in mid-aged and elderly Chinese: a cross-sectional study.

机构信息

Department of Graduate School, Wannan Medical College, Wuhu, Anhui, China.

Student Health Center, Wannan Medical College, Wuhu, Anhui, China.

出版信息

BMC Geriatr. 2024 Jan 20;24(1):77. doi: 10.1186/s12877-023-04650-2.

Abstract

OBJECTIVE

Hypertension refers to the persistent elevation of blood pressure above the established normal range, resulting in increased pressure exerted by blood on the walls of blood vessels during its circulation. Recent studies have identified significant associations between obesity and lipid-related indices, as well as hypertension. Nevertheless, these studies have yet to comprehensively examine the correlation between the two variables. Our objective is to identify the fat and lipid-related indices that have the strongest correlation with hypertension.

METHOD

There was a total of 9488 elderly and middle-aged Chinese citizens who participated in this investigation. The participants in this research were separated into distinct gender cohorts. The participants were classified into normal and hypertensive categories according to their gender, with hypertension defined as a blood pressure level of 140/90 mmHg or higher, or a history of hypertension. Through the utilization of binary logistic regression analyses and the receiver operator curve (ROC), the optimal among fourteen indicators associated with obesity and lipids were identified.

RESULTS

After adjusting for variables, statistical analysis showed that all 14 measures of obesity and lipid were risk factors for hypertension. The receiver operating characteristic (ROC) curve analysis reveals that the Chinese visceral adiposity index (CVAI) has the highest degree of relationship to hypertension. Simultaneously, a statistically significant association between hypertension and these 14 variables was observed in both males and females.

CONCLUSION

There was a significant independent association between various parameters related to obesity and lipid-related index and the presence of hypertension, indicating that these factors can be considered risk factors for hypertension. CVAI and WHtR (waist height ratio) can be used to screen the high-risk groups of hypertensions in middle-aged and elderly people in China, and then take individualized health care measures to reduce the harm of hypertension.

摘要

目的

高血压是指血压持续高于既定正常范围,导致血液在循环过程中对血管壁施加的压力增加。最近的研究已经确定肥胖和与脂质相关的指数与高血压之间存在显著关联。然而,这些研究尚未全面检查这两个变量之间的相关性。我们的目的是确定与高血压相关性最强的脂肪和脂质相关指标。

方法

共有 9488 名中国中老年公民参与了这项调查。研究对象分为不同的性别队列。根据性别将研究对象分为正常和高血压组,高血压定义为血压水平为 140/90mmHg 或更高,或有高血压病史。通过二元逻辑回归分析和接收者操作特征(ROC)曲线,确定与肥胖和脂质相关的 14 个指标中的最佳指标。

结果

在调整变量后,统计分析表明,肥胖和脂质的所有 14 项指标都是高血压的危险因素。ROC 曲线分析表明,中国内脏脂肪指数(CVAI)与高血压的相关性最高。同时,在男性和女性中,高血压与这 14 个变量之间均存在统计学显著关联。

结论

肥胖和与脂质相关的指数与高血压之间存在显著的独立关联,表明这些因素可被视为高血压的危险因素。CVAI 和 WHtR(腰高比)可用于筛查中国中老年高血压高危人群,然后采取个性化的保健措施,降低高血压的危害。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4335/10800050/0ec9ea07c06b/12877_2023_4650_Fig1_HTML.jpg

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