Anantha-Krishnan Ahilan, Myers Casey A, Fitzpatrick Clare K, Clary Chadd W
Center of Orthopaedic Biomechanics, University of Denver, Denver, CO 80208, USA.
Mechanical and Biomedical Engineering, Boise State University, Boise, ID 83725, USA.
Bioengineering (Basel). 2023 Dec 28;11(1):37. doi: 10.3390/bioengineering11010037.
Subject-specific hip capsule models could offer insights into impingement and dislocation risk when coupled with computer-aided surgery, but model calibration is time-consuming using traditional techniques. This study developed a framework for instantaneously generating subject-specific finite element (FE) capsule representations from regression models trained with a probabilistic approach. A validated FE model of the implanted hip capsule was evaluated probabilistically to generate a training dataset relating capsule geometry and material properties to hip laxity. Multivariate regression models were trained using 90% of trials to predict capsule properties based on hip laxity and attachment site information. The regression models were validated using the remaining 10% of the training set by comparing differences in hip laxity between the original trials and the regression-derived capsules. Root mean square errors (RMSEs) in laxity predictions ranged from 1.8° to 2.3°, depending on the type of laxity used in the training set. The RMSE, when predicting the laxity measured from five cadaveric specimens with total hip arthroplasty, was 4.5°. Model generation time was reduced from days to milliseconds. The results demonstrated the potential of regression-based training to instantaneously generate subject-specific FE models and have implications for integrating subject-specific capsule models into surgical planning software.
特定于个体的髋关节囊模型与计算机辅助手术相结合时,可提供有关撞击和脱位风险的见解,但使用传统技术进行模型校准非常耗时。本研究开发了一个框架,用于从采用概率方法训练的回归模型中即时生成特定于个体的有限元(FE)囊表示。对植入髋关节囊的经过验证的有限元模型进行概率评估,以生成将囊几何形状和材料特性与髋关节松弛度相关联的训练数据集。使用90%的试验训练多元回归模型,以根据髋关节松弛度和附着部位信息预测囊特性。通过比较原始试验与回归衍生囊之间髋关节松弛度的差异,使用训练集的其余10%对回归模型进行验证。根据训练集中使用的松弛度类型,松弛度预测中的均方根误差(RMSE)范围为1.8°至2.3°。在预测从五个全髋关节置换尸体标本测量的松弛度时,RMSE为4.5°。模型生成时间从数天缩短至毫秒。结果证明了基于回归的训练即时生成特定于个体的有限元模型的潜力,并对将特定于个体的囊模型集成到手术规划软件中具有启示意义。