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精油和防腐剂(葡萄糖酸洗必泰和聚维酮碘)对从马伤口分离出的细菌的体外作用

In Vitro Effect of Essential Oils and Antiseptics (Chlorhexidine Gluconate and Povidone-Iodine) against Bacterial Isolates from Equine Wounds.

作者信息

Pimenta José, Dias Carla, Cotovio Mário, Saavedra Maria José

机构信息

Department of Veterinary Sciences, Antimicrobials, Biocides & Biofilms Unit (A2BUnit), University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal.

CECAV-Veterinary and Animal Research Center and Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), University of Trás-os-Montes e Alto Douro, 5000-801 Vila Real, Portugal.

出版信息

Vet Sci. 2023 Dec 26;11(1):12. doi: 10.3390/vetsci11010012.

Abstract

Considering the increasing antibiotics resistance, there has been a propensity to replace them with antiseptics when it comes to wound management and treatment. Nevertheless, in recent years, there have been reports regarding resistance to antiseptics by some bacterial strains. There is also concern about the environmental impact of these substances. The aim of this study was to compare the antimicrobial efficacy of antiseptics and eucalyptus essential oils on bacterial strains from horse's wounds. We used twelve , eight , two , one and one strains from equine wounds. The effect of essential oil, essential oil, povidone-iodine and chlorhexidine gluconate against the isolated strains was evaluated applying the Kirby-Baüer method. Regarding the strains, and the mixture of and had a better inhibitory effect than antiseptics. had a better effect against most spp. compared to . For both Gram-negative and Gram-positive strains tested, chlorhexidine gluconate had a better inhibitory effect than povidone-iodine. The antibacterial efficacy of essential oils highlights their potential to substitute or complement the use of antiseptics and so reduce resistance to antiseptics.

摘要

考虑到抗生素耐药性不断增加,在伤口处理和治疗方面,人们倾向于用防腐剂替代抗生素。然而,近年来,有报道称一些细菌菌株对防腐剂产生了耐药性。人们还担心这些物质对环境的影响。本研究的目的是比较防腐剂和桉树精油对马伤口细菌菌株的抗菌效果。我们使用了来自马伤口的12株、8株、2株、1株和1株菌株。应用 Kirby-Baüer 方法评估了[具体精油名称1]精油、[具体精油名称2]精油、聚维酮碘和葡萄糖酸洗必泰对分离菌株的作用。对于[具体菌株类型1]菌株,[具体精油名称1]以及[具体精油名称1]和[具体精油名称2]的混合物比防腐剂具有更好的抑制作用。与[某防腐剂名称]相比,[具体精油名称2]对大多数[具体菌株类型2]菌有更好的效果。对于所测试的革兰氏阴性和革兰氏阳性菌株,葡萄糖酸洗必泰比聚维酮碘具有更好的抑制作用。精油的抗菌效果突出了它们替代或补充防腐剂使用从而降低对防腐剂耐药性的潜力。

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本文引用的文献

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