Karbach J, Ebenezer S, Warnke P H, Behrens E, Al-Nawas B
Clin Lab. 2015;61(1-2):61-8. doi: 10.7754/clin.lab.2014.140714.
The aim of the study was to examine the in vitro antibacterial activity of different oils in comparison to antiseptics against oral microorganisms.
The antimicrobial effect of tea tree oil (TTO), eucalyptus oil (EO), lemon grass oil (LGO), and a eucalyptus-based oil mixture (MXT) were tested in comparison to chlorhexidine digluconate (CHX), povidone-iodine (BTA), and octenidine dihydrochloride (OCT). Oral bacterial strains and candida species using the agar diffusion test were used for the antimicrobial study.
All tested oils showed antimicrobial potency against the tested biological indicators. In comparison of all tested substances the largest effective zones were measured for LGO, followed from MXT and CHX. TTO and EO were less effective against the tested microorganisms followed from BTA.
The results of this study show that some essential oils have better antimicrobial properties than standard oral antiseptics. In a follow-up step, the ideal concentrations, the composition of essential oils, and the mode of application will be evaluated. The antibacterial efficacy of essential oils might be promising for use in clinical and oral hygiene applications. The cost reduction and availability particularly in rural areas with easy access to the originating plants might be advantageous factors to be considered.
本研究的目的是比较不同的油类与防腐剂对口腔微生物的体外抗菌活性。
与葡萄糖酸洗必泰（CHX）、聚维酮碘（BTA）和二盐酸奥替尼啶（OCT）相比，测试了茶树油（TTO）、桉叶油（EO）、柠檬草油（LGO）和一种基于桉叶油的混合油（MXT）的抗菌效果。使用琼脂扩散试验对口腔细菌菌株和念珠菌进行抗菌研究。
所有测试油类均对测试的生物指标显示出抗菌效力。在所有测试物质中，LGO的有效抑菌圈最大，其次是MXT和CHX。TTO和EO对测试微生物的效果较差，其次是BTA。
本研究结果表明，一些精油具有比标准口腔防腐剂更好的抗菌性能。在后续步骤中，将评估理想浓度、精油成分和应用方式。精油的抗菌功效在临床和口腔卫生应用中可能很有前景。成本降低以及在容易获取原生植物的农村地区的可得性可能是需要考虑的有利因素。
