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一种用于表征可持续生产的天然靛蓝颜料的连续萃取方案。

A Continuous Extraction Protocol for the Characterisation of a Sustainably Produced Natural Indigo Pigment.

作者信息

Frignani Elia, D'Eusanio Veronica, Grandi Mauro, Pigani Laura, Roncaglia Fabrizio

机构信息

Department of Chemical and Geological Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.

National Interuniversity Consortium of Materials Science and Technology (INSTM), 50121 Firenze, Italy.

出版信息

Life (Basel). 2023 Dec 29;14(1):59. doi: 10.3390/life14010059.

DOI:10.3390/life14010059
PMID:38255674
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10817639/
Abstract

The sustainable industrial production of indigo necessitates a unique extraction process to separate the plant-derived compounds. Calcium compounds are added to encourage hydrolysis of these precursors and to facilitate the isolation of the final form, resulting in an organic-inorganic composite pigment with unspecified characteristics. In this study, we devised a continuous solvent extraction procedure to fractionate the organic indigoid phase within the composite pigment. Overcoming challenges posed by limited solubility in the common organic solvents, this method allows for the analysis of individual fractions, significantly enhancing resolution. Comprehensive characterisation using spectroscopic analysis, thermogravimetry, and UHPLC-MS/MS revealed the potential for quantifying primary components of the natural pigment and distinct differentiation from the synthetic dye. This approach also holds promise for establishing robust manufacturing practices in the industrial production of natural indigo.

摘要

靛蓝的可持续工业生产需要独特的提取工艺来分离植物衍生化合物。添加钙化合物以促进这些前体的水解，并便于分离最终形式，从而得到具有未指定特性的有机-无机复合颜料。在本研究中，我们设计了一种连续溶剂萃取程序，以分离复合颜料中的有机靛蓝相。该方法克服了在常见有机溶剂中溶解度有限所带来的挑战，能够对各个馏分进行分析，显著提高了分辨率。使用光谱分析、热重分析和超高效液相色谱-串联质谱进行的综合表征揭示了定量天然色素主要成分的潜力，以及与合成染料的明显区分。这种方法也有望在天然靛蓝的工业生产中建立稳健的制造工艺。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b67/10817639/757d89d3ffb9/life-14-00059-g010.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b67/10817639/8cd4b042ce24/life-14-00059-g008.jpg
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