Hosseini Mohsen, Huang Jinge, Williams Myra D, Gonzalez Gerardo Alexander, Jiang Xiuping, Falkinham Joseph O, Ducker William A
Department of Chemical Engineering, Center for Soft Matter and Biological Physics, Virginia Tech, Blacksburg, VA 24061, USA.
Department of Food, Nutrition, and Packaging Sciences, Clemson University, Clemson, SC 29634, USA.
Microorganisms. 2023 Dec 31;12(1):83. doi: 10.3390/microorganisms12010083.
Antimicrobial coatings can inhibit the transmission of infectious diseases when they provide a quick kill that is achieved long after the coating application. Here, we describe the fabrication and testing of a glass coating containing AgO microparticles that was prepared from sodium silicate at room temperature. The half-lives of both methicillin-resistant (MRSA) and on this coating are only 2-4 min. The half-life of spores is about 9-12 min, which is extremely short for a spore. Additional tests on MRSA demonstrate that the coating retains its antimicrobial activity after abrasion and that an increased loading of AgO leads to a shorter half-life. This coating combines the properties of optical transparency, robustness, fast kill, and room temperature preparation that are highly desirable for an antimicrobial coating.
抗菌涂层在应用后很长时间仍能实现快速杀菌时，可抑制传染病的传播。在此，我们描述了一种含AgO微粒的玻璃涂层的制备与测试，该涂层是在室温下由硅酸钠制备而成。耐甲氧西林金黄色葡萄球菌（MRSA）和[此处原文缺失部分内容]在这种涂层上的半衰期仅为2 - 4分钟。孢子的半衰期约为9 - 12分钟，这对于孢子来说极短。对MRSA的进一步测试表明，该涂层在磨损后仍保持其抗菌活性，并且AgO负载量增加会导致半衰期缩短。这种涂层兼具光学透明性、坚固性、快速杀菌和室温制备等特性，这些都是抗菌涂层非常理想的性能。
