Maruyama Tomoya, Ishiguro Takashi, Takano Kenji, Shimizu Yoshihiko
Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Saitama, Japan.
Department of Pathology, Saitama Cardiovascular and Respiratory Center, Saitama, Japan.
Respir Med Case Rep. 2023 Dec 29;47:101972. doi: 10.1016/j.rmcr.2023.101972. eCollection 2024.
A 62-year-old woman presented with chronic cough. Chest CT showed multiple nodules and consolidation. Bronchoscopy could not confirm a specific diagnosis. Because her symptoms and lung opacities improved spontaneously, she was followed without treatment. Seven months later, chest radiography showed worsening of consolidation and a tumorous shadow. After performing cervical lymph node and lung tissue biopsies, we diagnosed her as having angioimmunoblastic T-cell lymphoma (AITL). Cases of AITL showing migration of lung shadows have not been reported. AITL development is influenced by immunodeficiency and reactivation of EBV, and migration of lung opacities may be related to the patient's immune status.
一名62岁女性因慢性咳嗽就诊。胸部CT显示多个结节及实变影。支气管镜检查未能确诊。因其症状及肺部阴影自行改善,故未治疗而进行随访。七个月后,胸部X线显示实变加重及肿瘤样阴影。经颈部淋巴结及肺组织活检后,我们诊断她患有血管免疫母细胞性T细胞淋巴瘤(AITL)。尚未有AITL出现肺部阴影游走的病例报道。AITL的发生受免疫缺陷及EBV再激活影响,肺部阴影的游走可能与患者的免疫状态有关。