Kagle D M, Alexander C M, Berko R S, Giuffre M, Gross J B
Anesthesiology. 1987 Mar;66(3):376-80. doi: 10.1097/00000542-198703000-00018.
The authors determined the accuracy of the Ohmeda 3700 (version J) pulse oximeter in healthy volunteers rendered hypoxic (SaO2 from 60-98%) by breathing mixtures of O2 in N2. When equipped with an ear probe, the pulse oximeter reading (y) reliably predicted arterial saturation (x) under steady-state conditions (y = 1.05x - 4.66, r = 0.98) as well as when oxygen saturation was rapidly decreasing (y = 1.05x - 6.38, r = 0.96). Conversely, when equipped with a finger probe, the oximeter tended to significantly underestimate steady-state arterial saturation (y = 1.21x - 19.1, r = 0.98, P less than 0.001). In response to this information, the manufacturer modified the oximeter's software (version XJ1), resulting in improved agreement between oximeter readings and arterial values (y = 0.96x + 4.59, r = 0.99). Despite the close correlation between steady-state oximeter readings and arterial saturation, the 99% prediction limits for both the ear and finger probes (version XJ1) were +/- 8%. Finger probe readings did not reliably reflect radial arterial oxygenation during rapid desaturation (y = 0.55x + 45.2, r = 0.78). This may be related to the time required to "arterialize" the blood in the finger; during acute resaturation, we found that the ear- to finger-probe delay was 24.0 +/- 2.3 s (means +/- SE, P less than 0.001).
作者通过让健康志愿者吸入氮气和氧气的混合气体来使其处于低氧状态(动脉血氧饱和度从60%至98%),从而测定了Ohmeda 3700(J版)脉搏血氧仪的准确性。当配备耳部探头时,在稳态条件下(y = 1.05x - 4.66,r = 0.98)以及血氧饱和度快速下降时(y = 1.05x - 6.38,r = 0.96),脉搏血氧仪读数(y)能够可靠地预测动脉血氧饱和度(x)。相反,当配备手指探头时,血氧仪往往会显著低估稳态动脉血氧饱和度(y = 1.21x - 19.1,r = 0.98,P小于0.001)。基于此信息,制造商对血氧仪软件进行了修改(XJ1版),使得血氧仪读数与动脉值之间的一致性得到改善(y = 0.96x + 4.59,r = 0.99)。尽管稳态血氧仪读数与动脉血氧饱和度之间存在密切相关性,但耳部和手指探头(XJ1版)的99%预测限均为±8%。在快速去饱和过程中,手指探头读数不能可靠地反映桡动脉的氧合情况(y = 0.55x + 45.2,r = 0.78)。这可能与手指血液“动脉化”所需的时间有关;在急性再饱和过程中,我们发现耳部探头与手指探头之间的延迟为24.0±2.3秒(均值±标准误,P小于0.001)。