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吸入原油蒸气的毒理学效应。

Toxicological Effects of Inhaled Crude Oil Vapor.

机构信息

Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV, 26505, USA.

出版信息

Curr Environ Health Rep. 2024 Mar;11(1):18-29. doi: 10.1007/s40572-024-00429-8. Epub 2024 Jan 24.

Abstract

PURPOSE OF REVIEW

The purpose of this review is to assess the toxicological consequences of crude oil vapor (COV) exposure in the workplace through evaluation of the most current epidemiologic and laboratory-based studies in the literature.

RECENT FINDINGS

Crude oil is a naturally occuring mixture of hydrocarbon deposits, inorganic and organic chemical compounds. Workers engaged in upstream processes of oil extraction are exposed to a number of risks and hazards, including getting crude oil on their skin or inhaling crude oil vapor. There have been several reports of workers who died as a result of inhalation of high levels of COV released upon opening thief hatches atop oil storage tanks. Although many investigations into the toxicity of specific hydrocarbons following inhalation during downstream oil processing have been conducted, there is a paucity of information on the potential toxicity of COV exposure itself. This review assesses current knowledge of the toxicological consequences of exposures to COV in the workplace.

摘要

目的综述

本综述旨在通过评估文献中最新的流行病学和实验室研究,评估工作场所原油蒸气(COV)暴露的毒理学后果。

最近的发现

原油是一种天然存在的碳氢化合物沉积物、无机和有机化合物的混合物。从事石油开采上游过程的工人面临许多风险和危害,包括皮肤接触原油或吸入原油蒸气。有几起因打开储油罐顶部的检修孔时吸入大量 COV 而导致工人死亡的报告。尽管已经对下游石油加工过程中吸入特定碳氢化合物的毒性进行了许多调查,但关于 COV 暴露本身潜在毒性的信息却很少。本综述评估了目前对工作场所 COV 暴露的毒理学后果的认识。

相似文献

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Toxicological Effects of Inhaled Crude Oil Vapor.吸入原油蒸气的毒理学效应。
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本文引用的文献

3
Automated crude oil vapor inhalation exposure system.自动化原油蒸气吸入暴露系统。
Inhal Toxicol. 2022;34(11-12):340-349. doi: 10.1080/08958378.2022.2114562. Epub 2022 Aug 25.
4
Biological effects of inhaled crude oil vapor. II. Pulmonary effects.吸入原油蒸气的生物学效应。二、肺部效应。
Toxicol Appl Pharmacol. 2022 Sep 1;450:116154. doi: 10.1016/j.taap.2022.116154. Epub 2022 Jul 5.
6
Biological effects of inhaled crude oil. VI. Immunotoxicity.吸入原油的生物学效应。六、免疫毒性。
Toxicol Appl Pharmacol. 2022 Aug 15;449:116100. doi: 10.1016/j.taap.2022.116100. Epub 2022 Jun 6.
7
Biological effects of crude oil vapor. IV. Cardiovascular effects.原油蒸气的生物学效应。四、心血管效应。
Toxicol Appl Pharmacol. 2022 Jul 15;447:116071. doi: 10.1016/j.taap.2022.116071. Epub 2022 May 20.
8
A review of the toxicology of oil in vertebrates: what we have learned following the oil spill.油在脊椎动物体内的毒理学综述:溢油事件后的经验教训
J Toxicol Environ Health B Crit Rev. 2021 Nov 17;24(8):355-394. doi: 10.1080/10937404.2021.1975182. Epub 2021 Sep 19.
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Lung function in oil spill responders 4-6 years after the Deepwater Horizon disaster.深水地平线灾难后 4-6 年,石油泄漏应急人员的肺功能。
J Toxicol Environ Health A. 2020 Mar 18;83(6):233-248. doi: 10.1080/15287394.2020.1745111. Epub 2020 Apr 5.

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