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神经囊尾蚴病:成人癫痫发作的一个被忽视但可预防的病因。

Neurocysticercosis: A neglected but preventable cause of seizure in adults.

作者信息

Adjei Prosper, Obese Vida, Tang Richard, Manu Kingsley Owusu, Boateng Yaw Owusu Afriyie, Donkor Eunice Ansomah

机构信息

Department of Internal Medicine Methodist Hospital Wenchi Ghana.

Directorate of Internal Medicine Komfo Anokye Teaching Hospital Kumasi Ghana.

出版信息

Clin Case Rep. 2024 Jan 23;12(1):e8454. doi: 10.1002/ccr3.8454. eCollection 2024 Jan.

DOI:10.1002/ccr3.8454
PMID:38268622
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10805999/
Abstract

Neurocysticercosis is an infection of the central nervous system caused by the larval stage of . Although endemic in sub-Saharan Africa, it is neglected but remains a significant cause of preventable seizure in adults. Its diagnosis is challenging and is frequently missed due to its variable clinical manifestations and lack of diagnostic facilities in most areas of sub-Saharan Africa. This report discusses two cases of parenchymal neurocysticercosis in Ghanaians who presented to the emergency unit of a District Hospital with adult-onset seizures. The two cases highlight the need for a high index of suspicion and also underscore the important role of neuroimaging in the evaluation of patients presenting with adult-onset seizures in neurocysticercosis endemic areas. This is necessary for prompt detection and initiation of appropriate therapy in order to improve prognosis.

摘要

神经囊尾蚴病是由 的幼虫阶段引起的中枢神经系统感染。虽然在撒哈拉以南非洲地区流行,但它被忽视了,但仍然是成人可预防癫痫发作的重要原因。其诊断具有挑战性,由于其临床表现多样且撒哈拉以南非洲大部分地区缺乏诊断设施,经常被漏诊。本报告讨论了两名加纳人实质性神经囊尾蚴病的病例,他们因成人发作性癫痫到一家地区医院的急诊科就诊。这两个病例突出了高度怀疑的必要性,也强调了神经影像学在评估神经囊尾蚴病流行地区成人发作性癫痫患者中的重要作用。这对于及时检测和开始适当治疗以改善预后是必要的。 (原文中“由 的幼虫阶段引起”部分缺失关键信息)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d77/10805999/2e03cf88444d/CCR3-12-e8454-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d77/10805999/710e8e0c4c05/CCR3-12-e8454-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d77/10805999/383f76a10122/CCR3-12-e8454-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d77/10805999/1782de7bdf9b/CCR3-12-e8454-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d77/10805999/2e03cf88444d/CCR3-12-e8454-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d77/10805999/710e8e0c4c05/CCR3-12-e8454-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d77/10805999/383f76a10122/CCR3-12-e8454-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d77/10805999/1782de7bdf9b/CCR3-12-e8454-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d77/10805999/2e03cf88444d/CCR3-12-e8454-g002.jpg

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Carbamazepine versus levetiracetam in epilepsy due to neurocysticercosis.卡马西平与左乙拉西坦治疗脑囊虫病所致癫痫。
Acta Neurol Scand. 2021 Mar;143(3):242-247. doi: 10.1111/ane.13355. Epub 2020 Oct 22.
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Fake news in neglected tropical diseases: The case of neurocysticercosis.被忽视热带病领域的假新闻:神经囊尾蚴病案例
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Neurocysticercosis in people with epilepsy in Sub-Saharan Africa: A systematic review and meta-analysis of the prevalence and strength of association.撒哈拉以南非洲癫痫患者的神经囊尾蚴病:患病率及关联强度的系统评价和荟萃分析
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