Kwan Shu Hang, Gonzalez de Mejia Elvira
Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Champaign, IL 61801, USA.
Department of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, Champaign, IL 61801, USA.
Nutrients. 2024 Jan 22;16(2):329. doi: 10.3390/nu16020329.
Type 2 diabetes (T2D) is a common noncommunicable disease. In the United States alone, 37 million Americans had diabetes in 2017. The adzuki bean (), a legume, has been reported to possess antidiabetic benefits. However, the extent and specific mechanisms through which adzuki bean consumption may contribute to T2D prevention and management remain unclear. Therefore, the aim of this narrative review is to analyze current evidence supporting the utilization of adzuki beans in the diet as a strategy for preventing and managing T2D. Animal studies have demonstrated a positive impact of adzuki beans on managing T2D. However, supporting data from humans are limited. Conversely, the potential of adzuki bean consumption in preventing T2D via modulating two T2D risk factors (obesity and dyslipidemia) also lacks conclusive evidence. Animal studies have suggested an inconsistent and even contradictory relationship between adzuki bean consumption and the management of obesity and dyslipidemia, in which both positive and negative relationships are reported. In sum, based on the existing scientific literature, this review found that the effects of adzuki bean consumption on preventing and managing T2D in humans remain undetermined. Consequently, human randomized controlled trials are needed to elucidate the potential benefits of the adzuki bean and its bioactive components in the prevention and management of T2D.
2型糖尿病（T2D）是一种常见的非传染性疾病。仅在美国，2017年就有3700万美国人患有糖尿病。小豆（），一种豆类，据报道具有抗糖尿病的益处。然而，食用小豆可能有助于预防和管理2型糖尿病的程度和具体机制仍不清楚。因此，本叙述性综述的目的是分析目前支持在饮食中利用小豆作为预防和管理2型糖尿病策略的证据。动物研究已证明小豆对管理2型糖尿病有积极影响。然而，来自人类的支持数据有限。相反，通过调节两个2型糖尿病风险因素（肥胖和血脂异常）食用小豆预防2型糖尿病的潜力也缺乏确凿证据。动物研究表明，食用小豆与肥胖和血脂异常管理之间存在不一致甚至矛盾的关系，其中既有正相关也有负相关的报道。总之，基于现有科学文献，本综述发现食用小豆对人类预防和管理2型糖尿病的影响仍未确定。因此，需要进行人类随机对照试验，以阐明小豆及其生物活性成分在预防和管理2型糖尿病方面的潜在益处。
