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孟加拉国库什蒂亚新诊断的2型糖尿病(T2DM)患者中血脂异常及相关危险因素的患病率。

Prevalence of dyslipidemia and associated risk factors among newly diagnosed Type-2 Diabetes Mellitus (T2DM) patients in Kushtia, Bangladesh.

作者信息

Ahmmed Md Saad, Shuvo Suvasish Das, Paul Dipak Kumar, Karim M R, Kamruzzaman Md, Mahmud Niaz, Ferdaus Md Jannatul, Elahi Md Toufiq

机构信息

Bangladesh Institute of Research and Training on Applied Nutrition (BIRTAN), Jhenaidah, Bangladesh.

Department of Nutrition and Food Technology, Jashore University of Science and Technology, Jashore, Bangladesh.

出版信息

PLOS Glob Public Health. 2021 Dec 7;1(12):e0000003. doi: 10.1371/journal.pgph.0000003. eCollection 2021.

Abstract

Dyslipidemia is considered a significant modifiable risk factor for type-2 diabetes mellitus (T2DM) and has become one of the emerging health problems throughout the world. In Bangladesh, data on dyslipidemia among newly diagnosed T2DM patients are comparatively inadequate. This study aimed to evaluate the prevalence of dyslipidemia and its associated risk factors in newly diagnosed T2DM patients. This cross-sectional study was conducted by a well-structured questionnaire from 132 newly diagnosed type-2 diabetic patients attending the Mujibur Rahman Memorial Diabetic Hospital in Kushtia, Bangladesh. Data regarding socio-demographic, anthropometric, fasting blood glucose, total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL), and low-density lipoprotein (LDL) were collected from all the respondents. The association between dyslipidemia and its associated factors was analyzed using the multivariate logit regression model. The findings suggest that the prevalence rate of dyslipidemia was 75.7% in female and 72.6% in male T2DM patients. The odds of having dyslipidemia were 1.74 (95% Cl: 1.58-1.87) times significantly higher in female (p<0.001). The other factors associated with dyslipidemia encompassed age between 30-39 years (OR: 2.32, 95% CI: 1.97-2.69), obesity (OR: 2.63, 95% CI: 2.27-2.90), waist circumferences of male ≥90 and female ≥80 (OR: 1.65, 95% CI: 1.59-1.89), hypertensive patients (OR: 1.51, 95% CI: 1.45-1.74), physically inactive (OR: 3.25, 95% CI: 1.84-4.68), and current smoker or tobacco user (OR: 1.93, 95% CI: 1.85-2.13). This study concluded that the high prevalence of dyslipidemia was found among newly diagnosed type-2 diabetes patients and associated with gender, age, BMI, waist circumference, poor physical activity, and smoking, or tobacco use. This result will support increase awareness of dyslipidemia and its associated risk factors among type-2 diabetes patients.

摘要

血脂异常被认为是2型糖尿病(T2DM)一个重要的可改变风险因素,并且已成为全球新出现的健康问题之一。在孟加拉国,新诊断的T2DM患者中血脂异常的数据相对不足。本研究旨在评估新诊断的T2DM患者中血脂异常的患病率及其相关危险因素。这项横断面研究通过一份结构完善的问卷,对孟加拉国库什蒂亚穆吉布尔·拉赫曼纪念糖尿病医院的132例新诊断的2型糖尿病患者进行。从所有受访者收集了有关社会人口统计学、人体测量学、空腹血糖、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL)和低密度脂蛋白(LDL)的数据。使用多变量logit回归模型分析血脂异常与其相关因素之间的关联。研究结果表明,女性T2DM患者中血脂异常的患病率为75.7%,男性为72.6%。女性患血脂异常的几率显著高出1.74倍(95%置信区间:1.58 - 1.87)(p<0.001)。与血脂异常相关的其他因素包括年龄在30 - 39岁之间(比值比:2.32,95%置信区间:1.97 - 2.69)、肥胖(比值比:2.63,95%置信区间:2.27 - 2.90)、男性腰围≥90且女性腰围≥80(比值比:1.65,95%置信区间:1.59 - 1.89)、高血压患者(比值比:1.51,95%置信区间:1.45 - 1.74)、缺乏体育活动(比值比:3.25,95%置信区间:1.84 - 4.68)以及当前吸烟者或烟草使用者(比值比:1.93,95%置信区间:1.85 - 2.13)。本研究得出结论,新诊断的2型糖尿病患者中血脂异常患病率较高,且与性别、年龄、体重指数、腰围、体育活动不足以及吸烟或使用烟草有关。这一结果将有助于提高2型糖尿病患者对血脂异常及其相关危险因素的认识。

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