老年人对流感疫苗接种的记忆B细胞反应受损。 - Suppr

The memory B cell response to influenza vaccination is impaired in older persons.

作者信息

Burton Alice R, Guillaume Stephane M, Foster William S, Wheatley Adam K, Hill Danika L, Carr Edward J, Linterman Michelle A

出版信息

Cell Rep. 2024 Feb 27;43(2):113745. doi: 10.1016/j.celrep.2024.113745. Epub 2024 Jan 28.

DOI:10.1016/j.celrep.2024.113745

PMID:38281131

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10915395/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/487f/10915395/91b9d8901256/figs5.jpg

相似文献

The memory B cell response to influenza vaccination is impaired in older persons.老年人对流感疫苗接种的记忆B细胞反应受损。

Cell Rep. 2024 Feb 27;43(2):113745. doi: 10.1016/j.celrep.2024.113745. Epub 2024 Jan 28.

Impaired Memory B-Cell Response to Influenza Immunization in Patients With Common Variable Immunodeficiency (CVID).常见可变免疫缺陷（CVID）患者对流感疫苗接种的记忆B细胞反应受损。

Pathog Immun. 2021 Oct 27;6(2):105-118. doi: 10.20411/pai.v6i2.405. eCollection 2021.

Influenza vaccine-mediated protection in older adults: Impact of influenza infection, cytomegalovirus serostatus and vaccine dosage.老年人中流感疫苗介导的保护作用：流感感染、巨细胞病毒血清状态和疫苗剂量的影响。

Exp Gerontol. 2018 Jul 1;107:116-125. doi: 10.1016/j.exger.2017.09.015. Epub 2017 Sep 27.

Impact of ageing and a synbiotic on the immune response to seasonal influenza vaccination; a randomised controlled trial.衰老和共生元对季节性流感疫苗免疫反应的影响：一项随机对照试验。

Clin Nutr. 2018 Apr;37(2):443-451. doi: 10.1016/j.clnu.2017.01.011. Epub 2017 Jan 28.

The impact of immunosenescence on humoral immune response variation after influenza A/H1N1 vaccination in older subjects.免疫衰老对老年受试者接种甲型H1N1流感疫苗后体液免疫反应变化的影响。

PLoS One. 2015 Mar 27;10(3):e0122282. doi: 10.1371/journal.pone.0122282. eCollection 2015.

Diminished antibody response to influenza vaccination is characterized by expansion of an age-associated B-cell population with low PAX5.流感疫苗接种后的抗体反应减弱的特征是，与年龄相关的 B 细胞群体扩增，其 PAX5 水平较低。

Clin Immunol. 2018 Aug;193:80-87. doi: 10.1016/j.clim.2018.02.003. Epub 2018 Feb 6.

Front Immunol. 2018 Mar 22;9:591. doi: 10.3389/fimmu.2018.00591. eCollection 2018.

The induction of CD80 and apoptosis on B cells and CD40L in CD4+ T cells in response to seasonal influenza vaccination distinguishes responders versus non-responders in healthy controls and aviremic ART-treated HIV-infected individuals.在健康对照者和接受抗逆转录病毒治疗且无病毒血症的HIV感染者中，季节性流感疫苗接种后B细胞上CD80和凋亡的诱导以及CD4+T细胞中CD40L的表达，可区分应答者和无应答者。

Vaccine. 2017 Feb 1;35(5):831-841. doi: 10.1016/j.vaccine.2016.12.026. Epub 2016 Dec 22.

Antibody but not memory B-cell responses are tuned-down in vertically HIV-1 infected children and young individuals being vaccinated yearly against influenza.在每年接种流感疫苗的垂直感染 HIV-1 的儿童和年轻个体中，抗体而非记忆 B 细胞反应被下调。

Vaccine. 2014 Feb 3;32(6):657-63. doi: 10.1016/j.vaccine.2013.12.008. Epub 2013 Dec 13.

Influenza vaccination-induced H3 stalk-reactive memory B-cell clone expansion.流感疫苗诱导的 H3 茎部反应性记忆 B 细胞克隆扩增。

Vaccine. 2023 Jan 27;41(5):1132-1141. doi: 10.1016/j.vaccine.2022.12.068. Epub 2023 Jan 6.

引用本文的文献

Multiplexed Antibody Sequencing and Profiling of the Human Hemagglutinin-specific Memory B Cell Response following Influenza Vaccination.流感疫苗接种后针对人类血凝素特异性记忆 B 细胞反应的多重抗体测序和分析。

J Immunol. 2024 Dec 1;213(11):1605-1619. doi: 10.4049/jimmunol.2400326.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The memory B cell response to influenza vaccination is impaired in older persons.

作者信息

出版信息

相似文献

引用本文的文献

文献检索

文件翻译

深度研究

Suppr 超能文献

相似文献

引用本文的文献