饥饿有助于向富足转变——铁体故事。
Starvation helps transition to abundance - a ferrosome story.
机构信息
Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
出版信息
Trends Microbiol. 2024 Mar;32(3):219-220. doi: 10.1016/j.tim.2024.01.006. Epub 2024 Jan 28.
Abstract
Iron is an essential nutrient for bacterial pathogenesis. In their study, Skaar and colleagues (Pi et al.) discovered and determined the detailed structure of ferrosomes within Clostridioides difficile, the iron-storage organelles that form under iron-limited conditions in anticipation of future iron overload.
摘要
铁是细菌发病机制的必需营养素。在他们的研究中，Skaar 和同事们（Pi 等人）发现并确定了艰难梭菌中 Ferrosomes 的详细结构，这是一种在缺铁条件下形成的铁储存细胞器，以应对未来的铁过载。
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