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老年无症状纵隔成熟囊性畸胎瘤的手术治疗。

Surgical management of mediastinal mature cystic teratoma of the elderly remaining asymptomatic.

机构信息

Department of Thoracic surgery, Mohammed VI University Hospital, Marrakesh, Morocco.

出版信息

J Cardiothorac Surg. 2024 Jan 28;19(1):28. doi: 10.1186/s13019-024-02503-6.

DOI:10.1186/s13019-024-02503-6
PMID:38281986
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10822176/
Abstract

BACKGROUND

Mediastinal teratoma is an uncommon disease, nevertheless they represent the most common mediastinal germ cell tumors. It may grow silently for several years and remain undiagnosed until the occurrence of a complication.

AIM

The main aim of this article is to illustrate the silent evolution of an anterior mediastinal teratoma for over 70 years without presenting any notable complications.

CASE PRESENTATION

We present the case of a 70-year-old female, treated for hypertension referred to our department for managing a voluminous mediastinal mass, discovered fortuitously by a general practitioner in a chest X-ray. The anamnesis didn't relate any chest pain, cough, dyspnea nor hemoptysis. The clinical examination, in particular pleuropulmonary, was unremarkable. The workup (Chest X-Ray and CT scan) demonstrated a voluminous pleural mass at the expense of the right mediastinal pleura, rounded in shape, with calcified wall and fluid content. Blood tests did not demonstrate eosinophilia, and hydatid IgG serology was negative. serum human chorionic gonadotropin (hCG) and alpha fetoprotein (AFP) levels were found to be normal. The patient subsequently underwent a right posterolateral thoracotomy with resection of the lesion. The mass was dissected very carefully and then resected in toto. The macroscopic and microscopic histological examination demonstrated a mature cystic teratoma. Surgical resection was an adequate treatment and the prognosis was excellent for the patient.

CONCLUSION

Cystic mature teratomas are rare thoracic tumors, often recognized by radiological examination. This article relates the silent evolution that a teratoma could have, and the late appearance of symptoms that it could have.

摘要

背景

纵隔畸胎瘤是一种罕见的疾病,但它们是最常见的纵隔生殖细胞肿瘤。它可能在几年内无声地生长,并且在发生并发症之前一直未被诊断。

目的

本文的主要目的是说明一个前纵隔畸胎瘤 70 多年来无声演变而没有出现任何明显并发症的情况。

病例介绍

我们介绍了一位 70 岁女性的病例,她因高血压接受治疗,被转诊到我们科室治疗偶然发现的巨大纵隔肿块。这位患者没有任何胸痛、咳嗽、呼吸困难或咯血的病史。临床检查,特别是肺部,均无明显异常。检查(胸部 X 光和 CT 扫描)显示右侧纵隔胸膜上有一个巨大的胸膜肿块,呈圆形,有钙化壁和液体内容物。血液检查未显示嗜酸性粒细胞增多,并且囊虫 IgG 血清学为阴性。血清人绒毛膜促性腺激素(hCG)和甲胎蛋白(AFP)水平正常。随后,患者接受了右侧后外侧开胸术,切除了病变。小心地将肿块分离,然后整块切除。大体和显微镜下的组织学检查显示为成熟囊性畸胎瘤。手术切除是一种充分的治疗方法,对患者的预后极好。

结论

囊性成熟畸胎瘤是罕见的胸部肿瘤,通常通过影像学检查来识别。本文描述了畸胎瘤可能具有的无声演变,以及其可能出现的晚期症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/10822176/7247fd4b3224/13019_2024_2503_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/10822176/8a791800de95/13019_2024_2503_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/10822176/ad02331ee2a7/13019_2024_2503_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/10822176/8062da41eb1e/13019_2024_2503_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/10822176/7247fd4b3224/13019_2024_2503_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/10822176/8a791800de95/13019_2024_2503_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/10822176/ad02331ee2a7/13019_2024_2503_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/10822176/8062da41eb1e/13019_2024_2503_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba2/10822176/7247fd4b3224/13019_2024_2503_Fig4_HTML.jpg

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