Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune, 411018, Maharashtra, India.
Ir J Med Sci. 2024 Jun;193(3):1641-1650. doi: 10.1007/s11845-024-03617-5. Epub 2024 Jan 29.
Numerous scientific and medical domains have been revolutionized by nanotechnology, opening up unprecedented opportunities for healthcare applications. Among these developments, the creation of nanorobots for artificial blood components is a novel field of research that seeks to overcome the constraints of conventional pharmacological therapy. This review article provides a comprehensive overview of the nanorobotic artificial blood components and their therapeutic uses. The article begins by outlining the core concepts of nanotechnology and nanorobotic systems, emphasizing their design and control methods. It then delves into various types of nanorobotic artificial blood components, such as oxygen transporters (artificial RBCs), clotting agents (artificial platelets), and immune modulators (artificial WBCs). It goes into detail about their properties, functioning, and capabilities, which allow them to replicate the physiological activities of actual blood components. The article also assesses the clinical uses of artificial blood components in a variety of medical circumstances. It highlights their potential value in the management of certain blood-related diseases.
纳米技术已经彻底改变了众多科学和医学领域,为医疗应用带来了前所未有的机遇。在这些发展中,用于人造血液成分的纳米机器人的创造是一个寻求克服传统药物治疗限制的新研究领域。本文综述了纳米机器人人工血液成分及其治疗用途。文章首先概述了纳米技术和纳米机器人系统的核心概念,强调了它们的设计和控制方法。然后深入探讨了各种类型的纳米机器人人工血液成分,如氧气转运器(人工 RBC)、凝血剂(人工血小板)和免疫调节剂(人工白细胞)。详细介绍了它们的特性、功能和能力,这些特性、功能和能力使它们能够复制实际血液成分的生理活动。文章还评估了人工血液成分在各种医疗情况下的临床应用。强调了它们在某些与血液相关疾病的治疗中的潜在价值。