Kabul Elif Gur, Yenil Sinem, Ulutas Firdevs, Calik Bilge Basakci, Cobankara Veli
Faculty of Health Sciences, Physiotherapy and Rehabilitation, Usak University, Usak, Turkey.
Faculty of Physiotherapy and Rehabilitation, Pamukkale University, Denizli, Turkey.
Mediterr J Rheumatol. 2023 Aug 29;34(4):436-442. doi: 10.31138/mjr.290823.ib. eCollection 2023 Dec.
The aim of this study was to compare the effects of Behçet's disease in terms of anxiety, biopsychosocial status, fatigue, sleep quality, alexithymia, cognitive level, and quality of life according to major and minor organ involvement.
The study was planned as a single-centre cohort study. Fifty patients diagnosed with Behçet's (mean age 43±11.96 years) were included in the study. The patients were divided into two groups as major organ involvement (uveitis, neuro-Behçet's, or vascular type Behçet's disease) and minor organ involvement (mucocutaneous type Behçet's disease). Biopsychosocial status was evaluated with Biopsychosocial Questionnaire (BETY-BQ), anxiety with Beck Anxiety Inventory (BAI), fatigue with Multidimensional Assessment of Fatigue (MAF) Scale, sleep quality with Pittsburgh Sleep Quality Index (PSQI), alexithymia with Toronto Alexithymia Scale-20 (TAS-20), cognition level with Mini-Mental State Examination (MMSE), and quality of life with Short Form-36 (SF-36).
In the comparison according to minor and major organ involvement, there was no significant difference between the groups in BETY-BQ, BAI, MAF, PSQI, TAS-20, MMSE and SF-36 (p>0.05).
Behçet's disease negatively effects in parameters such as biopsychosocial status, fatigue, sleep quality, alexithymia and quality of life. The presence of major or minor organ involvement in the patients did not change these negative effects.
本研究旨在根据主要和次要器官受累情况,比较白塞病在焦虑、生物心理社会状态、疲劳、睡眠质量、述情障碍、认知水平和生活质量方面的影响。
本研究计划为单中心队列研究。纳入50例诊断为白塞病的患者(平均年龄43±11.96岁)。患者分为两组,即主要器官受累组(葡萄膜炎、神经白塞病或血管型白塞病)和次要器官受累组(黏膜皮肤型白塞病)。采用生物心理社会问卷(BETY-BQ)评估生物心理社会状态,采用贝克焦虑量表(BAI)评估焦虑,采用疲劳多维评估量表(MAF)评估疲劳,采用匹兹堡睡眠质量指数(PSQI)评估睡眠质量,采用多伦多述情障碍量表-20(TAS-20)评估述情障碍,采用简易精神状态检查表(MMSE)评估认知水平,采用简明健康状况调查量表(SF-36)评估生活质量。
根据次要和主要器官受累情况进行比较,两组在BETY-BQ、BAI、MAF、PSQI、TAS-20、MMSE和SF-36方面无显著差异(p>0.05)。
白塞病对生物心理社会状态、疲劳、睡眠质量、述情障碍和生活质量等参数有负面影响。患者主要或次要器官受累的情况并未改变这些负面影响。