Tolliver P R, Roe M H
Am J Clin Pathol. 1979 Aug;72(2):218-21. doi: 10.1093/ajcp/72.2.218.
Screening sera for streptococcal antibodies is a useful clinical procedure when recent streptococcal infection requires verification. Presently there are two test kits available that detect five (or more) of the antibodies that may be present. These two screening tests were compared using antistreptolysin O (ASO) and antideoxyribonuclease B (ADB) titers as the reference for true streptococcal infection. All four procedures were performed on 69 sera collected from a pediatric population. Both screening tests were found to be sensitive, specific, economical, and easy to perform; however, both were more sensitive to elevated ASO titers than to elevated ADB titers. In certain clinical situations, therefore, antibody titrations may be necessary to document completely recent streptococcal infection.
当需要确认近期是否感染链球菌时，检测血清中的链球菌抗体是一项有用的临床检查。目前有两种检测试剂盒，可检测可能存在的五种（或更多）抗体。以抗链球菌溶血素O（ASO）和抗脱氧核糖核酸酶B（ADB）滴度作为确诊链球菌感染的参考标准，对这两种筛查试验进行了比较。对从儿科人群中采集的69份血清进行了所有四种检测程序。结果发现，这两种筛查试验均具有敏感性、特异性、经济性且易于操作；然而，两者对ASO滴度升高的敏感性均高于对ADB滴度升高的敏感性。因此，在某些临床情况下，可能需要进行抗体滴定以全面记录近期的链球菌感染情况。
