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用于检测抗链球菌溶血素O抗体的筛查试验评估

Evaluation of screening tests for the detection of antistreptolysin O antibodies.

作者信息

Lue Y A, Nicolas C, Kemawikasit P, Pierre A, McLean T I, Simms D H

出版信息

J Clin Microbiol. 1983 Sep;18(3):628-30. doi: 10.1128/jcm.18.3.628-630.1983.

Abstract

The accuracy of two screening tests, one utilizing serum and the other utilizing whole blood, was compared with the accuracy of the conventional macrotitration method for the detection of antistreptolysin O antibodies. Of the 569 specimens tested with the serum screening procedure and the macrotitration method, 235 and 282, respectively, were positive for antistreptolysin O antibodies. Comparative testing of 200 specimens with the peripheral blood screening test and the macrotitration method gave 60.5% by the macrotitration procedure. Discrepant results with both procedures were obtained with specimens having 166 Todd units. The results suggest that these screening procedures can be used to screen specimens for the presence of significant antistreptolysin O antibodies.

摘要

比较了两种筛查试验(一种使用血清,另一种使用全血)检测抗链球菌溶血素O抗体的准确性与传统宏观滴定法的准确性。在用血清筛查程序和宏观滴定法检测的569份标本中,抗链球菌溶血素O抗体阳性的分别为235份和282份。用外周血筛查试验和宏观滴定法对200份标本进行比较检测,宏观滴定法得出的阳性率为60.5%。对于托德单位为166的标本,两种程序均得出了不一致的结果。结果表明,这些筛查程序可用于筛查标本中是否存在显著的抗链球菌溶血素O抗体。

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