Klonowski W, Epstein I R
Biophys J. 1987 Feb;51(2):249-53. doi: 10.1016/S0006-3495(87)83330-1.
We consider a model of actin-myosin interaction in which the sites belonging to each seven-site regulated actin unit are subdivided into two classes, "internal" and "external." The time evolution of each class of sites is considered separately, leading to a pair of coupled differential equations that may be integrated numerically. We also consider the critical sol-gel transition point for actin filaments crosslinked by two-headed heavy meromyosin (HMM). The possibility of new types of chemical oscillation and pattern formation arising from periodic sol-gel transitions is discussed.
我们考虑一种肌动蛋白-肌球蛋白相互作用模型，其中属于每个七位点调节肌动蛋白单元的位点被细分为两类，即“内部”和“外部”。分别考虑每类位点的时间演化，从而得到一对耦合的微分方程，可对其进行数值积分。我们还考虑了由双头重酶解肌球蛋白（HMM）交联的肌动蛋白丝的临界溶胶-凝胶转变点。讨论了周期性溶胶-凝胶转变产生新型化学振荡和图案形成的可能性。
