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[由微核组成的多核细胞中染色体核仁组织区的行为]

[Behavior of the nucleolus organizer regions of the chromosomes in polykaryocytes consisting of micronuclei].

作者信息

Stobetskiĭ V I, Mironova L L

出版信息

Biull Eksp Biol Med. 1987 Mar;103(3):346-7.

PMID:3828515
Abstract

The nucleolar organizer regions (NORs) of Chinese hamster chromosomes (clone 237, cell line BIId-ii-FAF28) were studied in mononuclear cells and polykaryocytes induced with colcemid. The chromosomes with NORs were marked as 1, 2, 3, 4. The activity of NORs in mononuclear cells was higher in chromosomes 1, 2, 3. The associations of NORs were observed between chromosomes I and 2 (3% of all metaphases). In polykaryocytes the chromosomal pairs 1, 2, 3 showed different NOR activity in different metaphases. The associations of NORs in pairs of chromosome I were found in 51.3% of cases. The associations of NORs in pairs of chromosome 2 were observed in 7.5% of cases. This method may be used for the estimation of association potency of NORs in chromosomes.

摘要

研究了秋水仙酰胺诱导的中国仓鼠染色体(克隆237,细胞系BIId-ii-FAF28)的核仁组织区(NORs)在单核细胞和多核细胞中的情况。带有NORs的染色体标记为1、2、3、4。在单核细胞中,1、2、3号染色体上NORs的活性较高。观察到1号和2号染色体之间存在NORs的联合(占所有中期相的3%)。在多核细胞中,1、2、3号染色体对在不同中期相表现出不同的NOR活性。在51.3%的病例中发现了1号染色体对中NORs的联合。在7.5%的病例中观察到2号染色体对中NORs的联合。该方法可用于评估染色体中NORs的联合能力。

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