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[非洲绿猴正常和转化脾细胞染色体核仁组织区的活性]

[Activity of the nucleolus-organizing regions of the chromosomes of normal and transformed spleen cells in the African green monkey].

作者信息

Khapchaev Iu Kh, Stobetskiĭ V I, Mironova L L

出版信息

Tsitologiia. 1985 Oct;27(10):1189-91.

PMID:4071663
Abstract

The activity of nucleolus organizer regions (NOR's) of chromosomes in the African green monkey cells has been studied before and after the transformation. In cells before their transformation, one or two chromosomes entering into association and possessing NORs are involved in the formation of one nucleolus. In transformed cells no correlation between the numbers of nucleoli in interphase and those of chromosomes possessing NORs was revealed in metaphase plates. It is supposed that in chromosomes of the transformed cells with faintly stained NORs the gene activity is preserved only in part.

摘要

对非洲绿猴细胞染色体的核仁组织区(NORs)在转化前后的活性进行了研究。在转化前的细胞中,一条或两条相互关联且具有NORs的染色体参与一个核仁的形成。在转化细胞中,间期核仁数量与中期板中具有NORs的染色体数量之间未发现相关性。据推测,在NORs染色浅的转化细胞染色体中,基因活性仅部分保留。

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