Panhuber H, Mackay-Sim A, Laing D G
Brain Res. 1987 Feb;428(2):307-11. doi: 10.1016/0165-3806(87)90129-5.
Adult sensory systems generally remain viable as long as stimulation or disease do not physically damage the sensors. Continuous exposure of adult rats to a single odor for two months, however, caused a shrinkage of mitral cells in the olfactory bulb which was more extensive and severe than found in adult rats exposed to deodorized air, or normal rat colony odors. The results suggest that lack of excitation of mitral cells may cause significant shrinkage (deodorized air treatment), but more severe shrinkage may occur through inhibition or masking by a single dominant odor in the environment. These results have implications for humans living or working in odorous environments.
只要刺激或疾病没有对传感器造成物理损伤，成年感觉系统通常就能保持正常功能。然而，成年大鼠连续两个月暴露于单一气味中，会导致嗅球中的二尖瓣细胞萎缩，这种萎缩比暴露于除臭空气中的成年大鼠或正常鼠群气味中的成年大鼠更为广泛和严重。结果表明，二尖瓣细胞缺乏兴奋可能会导致显著萎缩（除臭空气处理），但更严重的萎缩可能是由于环境中单一主导气味的抑制或掩盖所致。这些结果对生活或工作在有气味环境中的人类具有启示意义。
