The Warren Alpert Medical School of Brown University, Providence, Rhode Island.
J Nerv Ment Dis. 2024 Feb 1;212(2):129-131. doi: 10.1097/NMD.0000000000001737.
Early pubertal timing is associated with more adverse childhood experiences (ACEs) and increased risk for psychopathology during adolescence. However, most work to date has used community or epidemiological samples, and it remains unclear whether these associations persist in acute clinical samples. The present study examined associations between age at menarche and ACEs, psychiatric symptoms, and emotion regulation difficulties in a sample of N = 140 adolescents on a psychiatric inpatient unit. Youth with early menarche reported higher levels of depressive symptoms, more severe suicidal ideation, and greater difficulty with emotion regulation than youth with normative age at menarche. There was a marginal effect of youth with early menarche reporting more ACEs and more anxiety symptoms. These results suggest menarcheal age, and ACEs may be useful risk factors to assess in inpatient settings to predict risk for more severe outcomes, and future research on pubertal timing in high acuity settings is warranted.
青春期启动较早与更多的不良童年经历(ACEs)和青少年期精神病理学风险增加有关。然而,迄今为止大多数研究都使用了社区或流行病学样本,尚不清楚这些关联是否在急性临床样本中仍然存在。本研究在一个精神科住院病房的 N = 140 名青少年中,检查了初潮年龄与 ACEs、精神症状和情绪调节困难之间的关系。初潮较早的青少年报告的抑郁症状更严重,自杀意念更严重,情绪调节困难更大,而初潮正常的青少年则没有。初潮较早的青少年报告 ACEs 和焦虑症状较多,这具有边缘效应。这些结果表明,初潮年龄和 ACEs可能是评估住院环境中风险的有用危险因素,以预测更严重结局的风险,并且在高度严重的环境中研究青春期启动时间是合理的。