Chan C S, Pun W K, Chan Y M, Chow S P
Can J Anaesth. 1987 Jan;34(1):21-5. doi: 10.1007/BF03007677.
Lidocaine 0.5 per cent in a dose of 2 mg X kg-1 was used for intravenous regional analgesia with the tourniquet cuff placed over the forearm. The level of tourniquet cuff pressure employed was the arterial "occlusion pressure" plus 50 mmHg. In 48 normotensive patients successful analgesia was achieved; in seven hypertensive patients, four were pain-free, but the other three required more lidocaine to achieve adequate analgesia. No toxic symptoms and signs were observed. Measurement of serum lidocaine concentrations in 12 patients confirmed the safety of the technique, although small leakage of lidocaine past the inflated forearm tourniquet was detected in some patients.
将0.5%的利多卡因以2毫克/千克的剂量用于静脉区域镇痛，止血带袖带置于前臂上方。所采用的止血带袖带压力水平为动脉“闭塞压”加50毫米汞柱。48例血压正常的患者实现了成功镇痛；7例高血压患者中，4例无痛，但另外3例需要更多利多卡因才能实现充分镇痛。未观察到毒性症状和体征。对12例患者的血清利多卡因浓度进行测量证实了该技术的安全性，尽管在一些患者中检测到利多卡因有少量渗漏到充气的前臂止血带之外。
