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使用ExacTrac动态系统对头颈部放射治疗患者进行分次内运动监测的临床经验

Clinical Experience of Intrafractional Motion Monitoring of Patients Under Head and Neck Radiation Therapy Using ExacTrac Dynamic System.

作者信息

Chow Vivian U Y, Cheung Michael L M, Kan Monica W K, Chan Anthony T C

机构信息

Department of Clinical Oncology, Prince of Wales Hospital, Hong Kong SAR, China.

Department of Clinical Oncology, The Chinese University of Hong Kong, Hong Kong SAR, China.

出版信息

Adv Radiat Oncol. 2023 Oct 21;9(3):101390. doi: 10.1016/j.adro.2023.101390. eCollection 2024 Mar.

Abstract

PURPOSE

The combination of surface-guided radiation therapy (SGRT) and image-guided radiation therapy (IGRT) can provide complementary information of patient positioning throughout treatments. The ExacTrac Dynamic (EXTD) system is a combined SGRT and IGRT system that can provide real-time motion detection via optical surface and thermal tracking during treatment delivery, with stereoscopic x-ray for positional verification. The purpose of this study was to examine the performance of EXTD for intrafractional motion monitoring using real clinical cases.

METHODS AND MATERIALS

Treatment log files exported from EXTD for 40 patients with 335 fractions were retrospectively analyzed. Frequency of beam-hold triggered during treatments were recorded, with the comparison of shifts detected by optical surface tracking (EXTD_Thml) and x-ray verification (EXTD_Xray).

RESULTS

Among the 335 fractions, automatic beam-holds were triggered 41 times, followed by x-ray positional verification with internal anatomy. The difference of shifts detected by EXTD_Thml and EXTD_Xray were less than 1 mm and 1° in translational and rotational directions, respectively. After x-ray verification, none of them required the application of positional correction.

CONCLUSIONS

The availability of x-ray imaging with optical surface tracking in EXTD is essential to verify whether geometric shifts are required to correct patient position. Considering the ability of continuous monitoring of patient positions with optical surface tracking and internal imaging, EXTD is an effective tool for intrafractional motion monitoring during radiation therapy.

摘要

目的

表面引导放射治疗(SGRT)与图像引导放射治疗(IGRT)相结合可在整个治疗过程中提供患者定位的补充信息。ExacTrac Dynamic(EXTD)系统是一种结合了SGRT和IGRT的系统,在治疗过程中可通过光学表面和热追踪进行实时运动检测,并利用立体x光进行位置验证。本研究的目的是使用真实临床病例检验EXTD在分次治疗期间进行运动监测的性能。

方法和材料

对从EXTD导出的40例患者335个分次的治疗日志文件进行回顾性分析。记录治疗期间触发束流保持的频率,并比较通过光学表面追踪(EXTD_Thml)和x光验证(EXTD_Xray)检测到的位移。

结果

在335个分次中,自动束流保持触发了41次,随后对体内解剖结构进行了x光位置验证。EXTD_Thml和EXTD_Xray检测到的平移和旋转方向位移差异分别小于1毫米和1°。经过x光验证后,无一例需要进行位置校正。

结论

EXTD中x光成像与光学表面追踪相结合对于验证是否需要进行几何位移以校正患者位置至关重要。考虑到光学表面追踪和体内成像对患者位置的连续监测能力,EXTD是放射治疗期间分次治疗运动监测的有效工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4f0/10823086/c53ba48a0805/gr1.jpg

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