Universidade de São Paulo, School of Public Health - São Paulo (SP), Brazil.
Rev Bras Epidemiol. 2024 Jan 26;27:e240003. doi: 10.1590/1980-549720240003. eCollection 2024.
To assess the magnitude, trend, and spatial patterns of childhood and adolescent cancer mortality between 1996 and 2017 in 133 Brazilian intermediate regions by using socioeconomic and healthcare services indicators.
This is an ecological study for analyzing the trend of mortality from cancer in childhood and adolescence through time series. Data on deaths were extracted from the Brazilian Mortality Information System. Data on population were extracted from the 1991, 2000, and 2010 demographic censuses of the Brazilian Institute of Geography and Statistics, with interpolation for intercensal years. Time series were delineated for mortality by type of cancer in each intermediate region. Such regions were grouped by macroregions to present the results. The calculation and interpretation of mortality trends use the Prais-Winsten autoregression procedure.
Mortality rates for all neoplasms were higher in the Northern region (7.79 deaths per 100 thousand population), while for leukemias, they were higher in the Southern region (1.61 deaths per 100 thousand population). In both regions, mortality was higher in boys and in the 0-4 age group. The trend was decreasing (annual percent change [APC] - -2.11 [95%CI: -3.14; - 1.30]) for all neoplasms in the Brazilian regions and stationary (APC - -0.43 [95%CI: -1.61; 2.12]) for leukemias in the analyzed period.
The mortality rate for all neoplasms showed higher values in regions with smaller numbers of ICU beds in the public healthcare system.
利用社会经济和医疗保健服务指标，评估 1996 年至 2017 年期间巴西 133 个中级区域儿童和青少年癌症死亡率的幅度、趋势和空间模式。
这是一项生态研究，通过时间序列分析儿童和青少年癌症死亡率的趋势。死亡数据从巴西死亡率信息系统中提取。人口数据从巴西地理和统计研究所的 1991 年、2000 年和 2010 年人口普查中提取，并对期间年份进行插值。在每个中级区域，根据癌症类型划分死亡率时间序列。这些区域按大区分组，以呈现结果。使用普赖斯-温斯坦自回归程序计算和解释死亡率趋势。
所有肿瘤的死亡率在北部地区较高（每 10 万人中有 7.79 人死亡），而白血病的死亡率在南部地区较高（每 10 万人中有 1.61 人死亡）。在这两个地区，男孩和 0-4 岁年龄组的死亡率较高。趋势呈下降趋势（所有巴西地区的年变化百分比[APC]为-2.11%[95%CI：-3.14%；-1.30%]），分析期间白血病的趋势为稳定（APC 为-0.43%[95%CI：-1.61%；2.12%]）。
在公共医疗保健系统中 ICU 床位数量较少的地区，所有肿瘤的死亡率都较高。
