Zhao Meimei, Ma Jinrui, Yang Shuangyuan, Liu Hui, Wang Zhou, Zhao Yuxiang
Xi'an Medical University，Xi'an，710068，China.
Department of Otolaryngology Head and Neck Surgery，Shaanxi Provincial People's Hospital.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Feb;38(2):178-182. doi: 10.13201/j.issn.2096-7993.2024.02.019.
Chronic rhinosinusitis （CRS） is a common chronic inflammatory disease in otorhinolaryngology, in which eosinophilic chronic rhinosinusitis with nasal polyps represents the difficult-to-treat chronic rhinosinusitis （DTCRS） with poor prognosis. DTCRS has a poor prognosis, which seriously affects people's physical and mental health, and is treated with various means, including medication, biotherapy and surgery. In recent years, endoscopic sinus surgery and postoperative local administration of nasal hormones as one of its treatment methods have achieved good results. In this paper, we review the relevant literature at home and abroad and give an overview for the treatment means of surgery, focusing on the effect of endoscopic sinus surgery on the distributable range of postoperative nasal glucocorticosteroids in patients with DTCRS, and then on the postoperative efficacy of the treatment, with a view to providing a reference for the clinical treatment of DTCRS.
慢性鼻-鼻窦炎（CRS）是耳鼻咽喉科常见的慢性炎症性疾病，其中伴有鼻息肉的嗜酸性粒细胞性慢性鼻-鼻窦炎代表了预后较差的难治性慢性鼻-鼻窦炎（DTCRS）。DTCRS预后不良，严重影响人们的身心健康，临床上采用多种治疗手段，包括药物治疗、生物治疗和手术治疗。近年来，内镜鼻窦手术及术后局部应用鼻用激素作为其治疗方法之一取得了良好效果。本文通过回顾国内外相关文献，对手术治疗手段进行综述，重点阐述内镜鼻窦手术对DTCRS患者术后鼻用糖皮质激素分布范围的影响，进而探讨其术后治疗效果，以期为DTCRS的临床治疗提供参考。
