Wen Yanping, Fang Yezhen, Cao Feifei, Zhang Guozhong, Cheng Shi, Yu Yue, Huang Renjie, Ni Zhimin, Li Jun
Hangzhou Center for Disease Control and Prevention, Zhejiang, China.
Shangcheng District Center for Disease Control and Prevention, Zhejiang, China.
Heliyon. 2024 Jan 13;10(2):e24502. doi: 10.1016/j.heliyon.2024.e24502. eCollection 2024 Jan 30.
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease with sporadic occurrence and high mortality. Herein, we report an example of the in-hospital transmission of SFTS virus (SFTSV) infections with familial and nosocomial clustering in Zhejiang Province, eastern China, from March to April 2023. The epidemiological investigation and genomic analysis revealed that at least eight suspected cases of SFTS occurred in this cluster, including one death and one asymptomatic case. Our report reemphasizes the risk of familial and nosocomial SFTSV infections in healthcare settings and the urgent need for the long-term systematic surveillance of SFTSV evolution in humans and animals in the eastern coastal regions of China.
严重发热伴血小板减少综合征（SFTS）是一种新出现的蜱传传染病，呈散发性，死亡率高。在此，我们报告2023年3月至4月在中国东部浙江省发生的一起严重发热伴血小板减少综合征病毒（SFTSV）医院内传播事件，该事件呈现家族聚集性和医院聚集性。流行病学调查和基因组分析显示，该聚集性事件中至少出现8例SFTS疑似病例，包括1例死亡病例和1例无症状病例。我们的报告再次强调了医疗机构中SFTSV家族性和医院内感染的风险，以及对中国东部沿海地区人类和动物中SFTSV进化进行长期系统监测的迫切需要。
