Kępińska Adrianna P, Johnson Jessica S, Huckins Laura M
Pamela Sklar Division of Psychiatric Genomics, Icahn School of Medicine at Mount Sinai, New York, New York.
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York.
Biol Psychiatry Glob Open Sci. 2023 Aug 22;4(1):110-119. doi: 10.1016/j.bpsgos.2023.08.007. eCollection 2024 Jan.
Open science ensures that research is transparently reported and freely accessible for all to assess and collaboratively build on. Psychiatric genetics has led among the health sciences in implementing some open science practices in common study designs, such as replication as part of genome-wide association studies. However, thorough open science implementation guidelines are limited and largely not specific to data, privacy, and research conduct challenges in psychiatric genetics. Here, we present a primer of open science practices, including selection of a research topic with patients/nonacademic collaborators, equitable authorship and citation practices, design of replicable, reproducible studies, preregistrations, open data, and privacy issues. We provide tips for informative figures and inclusive, precise reporting. We discuss considerations in working with nonacademic collaborators and distributing research through preprints, blogs, social media, and accessible lecture materials. Finally, we provide extra resources to support every step of the research process.
开放科学确保研究能够得到透明的报告，所有人都可以免费获取以进行评估并在此基础上开展合作。在实施一些常见研究设计中的开放科学实践方面，精神遗传学在健康科学领域处于领先地位，比如将重复研究作为全基因组关联研究的一部分。然而，全面的开放科学实施指南有限，而且在很大程度上并未针对精神遗传学中数据、隐私和研究行为方面的挑战。在此，我们介绍开放科学实践入门知识，包括与患者/非学术合作者共同选择研究课题、公平的作者身份和引用规范、可重复研究的设计、预注册、开放数据以及隐私问题。我们提供制作信息丰富的图表以及进行全面、精确报告的小贴士。我们讨论与非学术合作者合作以及通过预印本、博客、社交媒体和通俗易懂的讲座材料传播研究成果时的注意事项。最后，我们提供额外资源以支持研究过程的每一步。
