Department of Pathogen Biology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China.
Key Laboratory of Antibody Engineering of Guangdong Higher Education Institutes, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou 510515, China.
Anal Methods. 2024 Feb 15;16(7):971-978. doi: 10.1039/d3ay01795h.
Virus-based human infectious diseases have a significant negative impact on people's health and social development. The need for quick, accurate, and early viral infection detection in preventive medicine is expanding. A microfluidic control is particularly suitable for point-of-care-testing virus diagnosis due to its advantages of low sample consumption, quick detection speed, simple operation, multi-functional integration, small size, and easy portability. It is also thought to have significant development potential and a wide range of application prospects in the research on virus detection technology. In an effort to aid researchers in creating novel microfluidic tools for virus detection, this review highlights recent developments of droplet-based microfluidics in virus detection research and also discusses the challenges and opportunities for rapid virus detection.
基于病毒的人类传染病对人们的健康和社会发展有重大的负面影响。在预防医学中，对快速、准确和早期的病毒感染检测的需求正在扩大。由于微流控具有低样品消耗、快速检测速度、简单操作、多功能集成、小尺寸和易于携带等优点，特别适合用于即时检测病毒诊断。它也被认为在病毒检测技术的研究中有很大的发展潜力和广泛的应用前景。为了帮助研究人员开发用于病毒检测的新型微流控工具，本综述重点介绍了基于液滴的微流控技术在病毒检测研究中的最新进展，并讨论了快速病毒检测的挑战和机遇。
