Shanxi Key Laboratory of Biomedical Metal Materials, College of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.
Taikang Bybo Dental, Zhuhai, 519100, China.
J Mater Chem B. 2024 Feb 21;12(8):1973-1990. doi: 10.1039/d3tb02492j.
The treatment of chronic refractory wounds poses significant challenges and threats to both human society and the economy. Existing research studies demonstrate that electrical stimulation fosters cell proliferation and migration and promotes the production of cytokines that expedites the wound healing process. Presently, clinical settings utilize electrical stimulation devices for wound treatment, but these devices often present issues such as limited portability and the necessity for frequent recharging. A cutting-edge wound dressing employing the piezoelectric effect could transform mechanical energy into electrical energy, thereby providing continuous electrical stimulation and accelerating wound healing, effectively addressing these concerns. This review primarily reviews the selection of piezoelectric materials and their application in wound dressing design, offering a succinct overview of these materials and their underlying mechanisms. This study also provides a perspective on the current limitations of piezoelectric wound dressings and the future development of multifunctional dressings harnessing the piezoelectric effect.
慢性难治性创面的治疗给人类社会和经济带来了重大挑战和威胁。现有研究表明，电刺激促进细胞增殖和迁移，并促进细胞因子的产生，从而加速创面愈合过程。目前，临床中使用电刺激设备进行创面治疗，但这些设备通常存在便携性有限和频繁充电等问题。一种利用压电效应的新型创面敷料可以将机械能转化为电能，从而提供持续的电刺激，加速创面愈合，有效解决这些问题。本综述主要回顾了压电材料的选择及其在创面敷料设计中的应用，简要概述了这些材料及其作用机制。本文还探讨了压电性创面敷料的局限性和利用压电效应的多功能敷料的未来发展。
