Department of Mechanical Engineering, University of Victoria, Victoria, BC, Canada; Division of Medical Sciences, University of Victoria, 3800 Finnerty Road, Victoria, BC V8W 2Y2, Canada; Axolotl Biosciences, 3800 Finnerty Road, Victoria, BC V8W 2Y2, Canada; Centre for Advanced Materials and Technologies, University of Victoria, 3800 Finnerty Road, Victoria, BC V8W 2Y2, Canada; School of Biomedical Engineering, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Cell Stem Cell. 2024 Feb 1;31(2):151-152. doi: 10.1016/j.stem.2023.12.014.
3D printing human tissue models derived from stem cells provides an increasingly popular tissue engineering strategy for probing biological questions. Here Yan et al. demonstrate how this technology can be used to model mature human neural tissues with functional neural networks in healthy and disease states.
3D 打印源自干细胞的人类组织模型为探究生物学问题提供了一种日益流行的组织工程策略。在此,Yan 等人展示了如何利用这项技术在健康和疾病状态下模拟具有功能性神经网络的成熟人类神经组织。