Division of Head and Neck, Department of Surgical Oncology, Tata Memorial Center, Homi Bhabha National Institute (HBNI), Mumbai, India.
Department of Head and Neck Surgical Oncology, Bombay Hospital, Mumbai, India.
Eur Arch Otorhinolaryngol. 2024 Apr;281(4):1953-1960. doi: 10.1007/s00405-024-08471-w. Epub 2024 Feb 3.
Many studies on the quality of life (QoL) among the thyroid cancer survivors have shown conflicting results. This may be since many of these studies have not used thyroid cancer-specific questionnaires.
In our study we have translated the EORTC THY-34, validated and served it in a cross-sectional study to the assess the QoL among thyroid cancer patients free of disease during their routine follow-up. Patients were categorized based on the duration from treatment completion, ATA risk stratification, treatment received, number of RAI sessions and thyroid function status during analysis.
Overall, 220 thyroid cancer survivors were included in this study. In general, in the EORTC QLQ-C30, the global QoL of thyroid cancer patients were good with a mean score of 72.99. The highest score was that for social functioning (89.55). In the EORTC-THY34 all the patients in the cohort had relatively lower scores (on symptom scales). Overall, there was no difference in the QLQ-C30 and THY-34 QoL with respect to any of the categorization mentioned above. However, our thyroid cancer patients QoL scores were better and/or comparable to those in published literature and they were also better or comparable to the QoL of the general population those were available in literature.
There was no difference in the QoL scores based on various categories. To better understand the quality of life of these patients a prospective longitudinal study with baseline values and values at regular intervals might give us a better insight.
许多关于甲状腺癌幸存者生活质量（QoL）的研究结果相互矛盾。这可能是因为许多这些研究都没有使用甲状腺癌特异性问卷。
在我们的研究中，我们翻译了 EORTC THY-34，并在一项横断面研究中对其进行了验证，以评估在常规随访中无疾病的甲状腺癌患者的 QoL。根据治疗完成后的时间、ATA 风险分层、接受的治疗、RAI 治疗次数以及分析期间的甲状腺功能状态对患者进行分类。
总体而言，本研究纳入了 220 例甲状腺癌幸存者。一般来说，在 EORTC QLQ-C30 中，甲状腺癌患者的整体 QoL 较好，平均得分为 72.99。得分最高的是社会功能（89.55）。在 EORTC-THY34 中，所有患者的评分都相对较低（在症状量表上）。总体而言，在 QLQ-C30 和 THY-34 中，患者的 QoL 评分与上述任何分类均无差异。然而，我们的甲状腺癌患者的 QoL 评分比文献中报道的要好，与文献中报道的一般人群的 QoL 评分相比也更好或相当。
基于各种分类，QoL 评分没有差异。为了更好地了解这些患者的生活质量，前瞻性纵向研究可能会提供更好的见解，包括基线值和定期间隔的值。
