Department of Chemistry, Maynooth University, Co. Kildare, Ireland.
Department of Chemistry, Maynooth University, Co. Kildare, Ireland.
Environ Res. 2024 May 1;248:118391. doi: 10.1016/j.envres.2024.118391. Epub 2024 Feb 1.
Sulfonamides are a family of synthetic drugs with a broad-spectrum of antimicrobial activity. Like other antimicrobials, they have been found in aquatic environments, making their detection important. Herein, an electrochemical sensor was designed using tannic acid exfoliated few-layered MoS sheets, which were combined with a mixture of reduced graphene oxide (rGO) and graphite flakes (G). The rGO/G was formed using electrodeposition, by cycling from -0.5 to -1.5 V in an acidified sulfate solution with well dispersed GO and G. The exfoliated MoS sheets were drop cast over the wrinkled rGO/G surface to form the final sensor, GCE/rGO/G/ta-MoS. The mixture of rGO/G was superior to pure rGO in formulating the sensor. The fabricated sensor exhibited an extended linear range from 0.1 to 566 μM, with a LOD of 86 nM, with good selectivity in the presence of various salts found in water and structurally related drugs from the sulfonamide family. The sensor showed very good reproducibility with the RSD at 0.48 %, repeatability and acceptable long term stability over a 10-day period. Good recovery from both tap and river water was achieved, with recovery ranging from 90.4 to 98.9 % for tap water and from 83.5 to 94.4 % for real river water samples.
磺胺类药物是一类具有广谱抗菌活性的合成药物。与其他抗菌药物一样，它们已在水生环境中被发现，因此对其进行检测非常重要。本文设计了一种电化学传感器，该传感器使用单宁酸剥离的少层 MoS 片，与还原氧化石墨烯（rGO）和石墨薄片（G）的混合物结合使用。rGO/G 通过在酸化的硫酸盐溶液中从-0.5 到-1.5 V 循环沉积形成，该溶液中具有良好分散的 GO 和 G。剥离的 MoS 片被滴铸在皱缩的 rGO/G 表面上，形成最终的传感器 GCE/rGO/G/ta-MoS。rGO/G 的混合物在配制传感器方面优于纯 rGO。所制备的传感器在 0.1 至 566 μM 的范围内表现出扩展的线性范围，LOD 为 86 nM，在存在水中各种盐和磺酰胺类结构相关药物的情况下具有良好的选择性。该传感器具有非常好的重现性，其 RSD 为 0.48%，重复性好，在 10 天的时间内稳定性可接受。从自来水和河水都取得了良好的回收率，自来水的回收率范围为 90.4%至 98.9%，实际河水样品的回收率范围为 83.5%至 94.4%。
