Centre for Research in Agricultural Genomics (CRAG), Cerdanyola del Vallès (Bellaterra), 08193 Barcelona, Spain.
Institute of Agrifood Research and Technology (IRTA), Caldes de Montbui, 0814 Barcelona, Spain.
Bioinformatics. 2024 Feb 1;40(2). doi: 10.1093/bioinformatics/btae060.
Pedigree-based analyses' prime role is to unravel relationships between individuals in breeding programs and germplasms. This is critical information for decoding the genetics underlying main inherited traits of relevance, and unlocking the genotypic variability of a species to carry out genomic selections and predictions. Despite the great interest, current lineage visualizations become quite limiting in terms of public display, exploration, and tracing of traits up to ancestral donors. PERSEUS is a user-friendly, intuitive, and interactive web-based tool for pedigree visualizations represented as directed graph networks distributed using a force-repulsion method. The visualizations do not only showcase individual relationships among accessions, but also facilitate a seamless search and download of phenotypic traits along the pedigrees. PERSEUS is a promising tool for breeders and scientists, advantageous for evolutionary, genealogy, and diversity analyses among related accessions and species.
PERSEUS is freely accessible at https://bioinformatics.cragenomica.es/perseus and GitHub code is available at https://github.com/aranzana-lab/PERSEUS.
基于系谱的分析主要作用是揭示繁殖计划和种质资源中个体之间的关系。这是解码主要遗传性状相关遗传基础和揭示物种基因型变异性以进行基因组选择和预测的关键信息。尽管人们非常感兴趣，但目前的谱系可视化在公共展示、探索和追溯特征到祖先供体方面存在很大的局限性。PERSEUS 是一个用户友好、直观和交互式的基于网络的工具，用于可视化系谱，表现为使用力排斥方法分布的有向图网络。这些可视化不仅展示了个体之间的关系，还方便了沿着系谱无缝搜索和下载表型特征。PERSEUS 是一种有前途的工具，对于繁殖者和科学家来说，它有利于相关个体和物种之间的进化、系统发育和多样性分析。
PERSEUS 可在 https://bioinformatics.cragenomica.es/perseus 免费访问，GitHub 代码可在 https://github.com/aranzana-lab/PERSEUS 获得。
